"Chandraprabha Vati: A promising network pharmacology for Metabolic Syndrome"
Journal name: Journal of Ayurveda and Integrative Medicine
Original article title: Network pharmacology analysis of Chandraprabha Vati: A new hope for the treatment of Metabolic Syndrome
The Journal of Ayurveda and Integrative Medicine (JAIM) is an open-access publication promoting collaboration between Ayurveda, traditional medicine, and biomedicine, publishing research on integrative health sciences
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Original source:
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Prashant Dongre, Anuradha Majumdar
Journal of Ayurveda and Integrative Medicine:
(A monthly peer-reviewed publication)
Full text available for: Network pharmacology analysis of Chandraprabha Vati: A new hope for the treatment of Metabolic Syndrome
Year: 2024 | Doi: 10.1016/j.jaim.2024.100902
Copyright (license): CC BY-NC-ND 4.0
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Glossary definitions and references:
Scientific and Ayurvedic Glossary list for �"Chandraprabha Vati: A promising network pharmacology for Metabolic Syndrome"�. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Table:
Tables are used to present data in a structured format, often facilitating comparison and understanding. In the context of research, tables summarize findings, methodologies, or results in a concise manner, making complex information accessible and helping readers grasp significant trends or outcomes easily. They serve as visual aids in scientific communication.
2) Inflammation:
Inflammation is a biological response to harmful stimuli, such as pathogens or tissue damage, and is characterized by redness, swelling, heat, and pain. It plays a crucial role in the body's defense mechanisms but can become chronic, contributing to diseases like metabolic syndrome, diabetes, and cardiovascular issues if not properly regulated.
3) Drug:
A drug is a substance used for medical treatment to prevent, diagnose, or cure diseases or medical conditions. In pharmacology, drugs interact with biological systems to bring about a therapeutic effect. Understanding their mechanisms of action is essential for developing effective treatments and improving patient outcomes in various health conditions.
4) Activity:
In the scientific context, 'activity' refers to the effect or response elicited by a drug, compound, or biological entity when tested under controlled conditions. Activity can include therapeutic benefits, interactions with biological targets, or side effects, making it a vital component of pharmacological studies and drug development processes.
5) Pharmacology:
Pharmacology is the study of drugs, their properties, effects, mechanisms of action, and their uses in medicine. It encompasses various fields, including clinical, medicinal, and toxicology. Knowledge of pharmacology is crucial for understanding drug development, safe prescription practices, and the physiological responses to medications within the human body.
6) Disease:
A disease is a pathological condition of a bodily part, an organ, or system resulting from various causes, including infection, genetic defects, or environmental factors. Diseases can be acute or chronic and impact overall health. Understanding the underlying biology of diseases is vital for effective prevention, diagnosis, and treatment strategies.
7) Candraprabha (Candra-prabha):
Chandraprabha, a traditional Ayurvedic formulation, is used for alleviating various health issues and is particularly noted for its applications in managing diabetes, metabolic syndrome, and related complications. Its multi-ingredient composition is believed to provide a synergistic effect, addressing multiple pathways and mechanisms involved in these conditions.
8) Ayurveda (Ayus-veda):
Ayurveda is an ancient Indian system of medicine that emphasizes a holistic approach to health and wellness, integrating balance among body, mind, and spirit. It utilizes herbal remedies, lifestyle changes, and dietary adjustments to promote health and prevent illness, focusing on individualized treatment plans based on patients' specific needs.
9) Vati:
Vati refers to a type of Ayurvedic formulation that typically consists of herbal or mineral-based ingredients prepared in a ball or tablet form. Vati preparations are commonly used for their therapeutic effects, targeting a range of health issues, including metabolic disorders, digestive problems, and inflammation.
10) Study (Studying):
In a scientific context, a study refers to a systematic investigation aimed at discovering or confirming knowledge about a particular subject. Studies can involve clinical trials, observational research, or laboratory experiments. They are essential for advancing medical knowledge, providing evidence-based conclusions and informing clinical practice.
11) Indian:
The term Indian in this context relates to the cultural and scientific practices originating from India, especially in the fields of traditional medicine like Ayurveda. Understanding Indian methods offers insights into holistic health approaches, emphasizing harmony with nature and the interconnectedness of physical and mental health.
12) Medicine:
Medicine encompasses the science and practice of diagnosing, treating, and preventing illness. It includes various fields such as pharmacology, surgery, and holistic approaches. The goal of medicine is to improve health outcomes and enhance the quality of life through evidence-based practices and therapeutic interventions.
13) Sharman (Sarma, Sharma, Sarman):
Sharma is a common surname in India, often associated with scholars, practitioners, or researchers in various fields, including medicine and Ayurveda. Individuals with this surname may contribute significantly to the study and application of traditional medicinal practices, scholarship, and health-related research within Indian and global contexts.
14) Beta:
Beta often refers to a specific type involved in drug interactions within pharmacology, such as beta receptors in the adrenergic system. Understanding beta interactions is crucial in pharmacotherapy, as they play vital roles in cardiovascular and respiratory health, influencing drug development and therapeutic strategies.
15) India:
India is known for its rich history of traditional medicine, particularly Ayurveda. The country's diverse cultural and ethnic backgrounds enrich its medicinal practices, contributing to the global landscape of healthcare. Understanding India's medical contributions offers insights into complementary therapies and holistic health approaches.
16) Pharmacological:
Pharmacological pertains to pharmacology, focusing on the study of drug actions and interactions within biological systems. This includes understanding drug mechanisms, effects, side effects, and therapeutic applications. Pharmacological knowledge is essential for drug development, safe usage, and optimizing treatment based on individual patient needs.
17) Cyperus rotundus:
Cyperus rotundus, also known as nutgrass, is a medicinal plant commonly used in traditional systems like Ayurveda for its various health benefits, including anti-inflammatory and analgesic properties. Research into its pharmacological effects may provide insights into potential applications in treating conditions such as metabolic syndrome.
18) Science (Scientific):
Science represents the systematic study of the natural world through observation and experimentation. In healthcare, scientific inquiry drives advancements in medical therapies, ensuring treatments are evidence-based and effective, and helping bridge the gap between traditional practices and modern therapeutic strategies.
19) Acorus calamus:
Acorus calamus, commonly known as sweet flag, is a herb traditionally used in Ayurveda for promoting cognitive function and various health benefits. Research into its pharmacological properties may reveal new therapeutic applications, particularly in managing conditions related to anxiety or digestive health.
20) Mineral:
Minerals are essential inorganic substances required for various physiological processes in the body. In Ayurvedic medicine, certain minerals are used in formulations to enhance health and treat various conditions. Understanding the role of minerals in therapy can provide insights into optimizing their use in medicines.
21) Blood:
Blood is a vital fluid in the body that transports oxygen, nutrients, and other substances to cells while carrying waste products away. Its composition and characteristics are significant in understanding various health conditions and in the diagnosis and treatment of diseases such as metabolic syndrome.
22) Shilajit (Silajit, Shila-jit):
Shilajit is a natural substance found in the Himalayas, traditionally used in Ayurveda for its rejuvenating and healing properties. Rich in minerals and bioactive compounds, Shilajit is believed to support energy levels, cognitive function, and overall health, making it a significant component in Ayurvedic formulations.
23) Guggulu:
Guggulu, derived from Commiphora mukul, is a resin used in Ayurvedic medicine renowned for its therapeutic properties, particularly in treating obesity and metabolic conditions. Its active constituents are believed to aid in lipid metabolism and inflammation, contributing to holistic approaches in managing health issues.
24) Kumar:
Kumar is a common Indian surname often associated with various professionals, including those in the medical and research fields. Individuals with this surname may contribute to advancements in traditional and modern medicinal practices, helping bridge the gap between ancient knowledge and contemporary scientific research.
25) Yoga:
Yoga is a holistic practice originating from ancient India, focusing on physical, mental, and spiritual well-being through postures, breathing exercises, and meditation. It is increasingly recognized for its benefits in managing stress, improving health, and complementing traditional medicine approaches in chronic conditions like metabolic syndrome.
26) Commiphora wightii:
Commiphora wightii, commonly known as guggul, is a resinous plant used in Ayurvedic medicine for its anti-inflammatory and cholesterol-lowering properties. Its extracts are studied for their efficacy in managing metabolic disorders, emphasizing the significance of traditional herbs in contemporary healthcare applications.
27) Similarity:
Similarity in pharmacological contexts refers to the resemblance between compounds, which can influence their biological activity and interactions. Identifying similarities among drugs or active constituents aids in predicting their efficacy and safety profiles, facilitating the development of effective therapeutic agents in modern medicine.
28) Family:
In biology, family refers to a taxonomic category, grouping related organisms that share common characteristics. Understanding the family relationships among medicinal plants can provide insights into their similarities, potential therapeutic benefits, and how they might work synergistically within traditional medical systems like Ayurveda.
29) Rules:
Rules in scientific research refer to established guidelines or principles that govern experimentation, data interpretation, and conclusions drawn. Adhering to these rules ensures the rigor and validity of research findings, which is essential for scientific advancements and credible recommendations in healthcare.
30) Phytochemical:
Phytochemicals are bioactive compounds found in plants that possess medicinal properties. They are significant in research for their health benefits, contributing to the efficacy of herbal medicines. Understanding phytochemical profiles allows for the development of new therapeutic agents derived from natural sources.
31) Writing:
Writing in the scientific context refers to documenting research findings, methodologies, and discussions to communicate knowledge effectively. Clear and precise writing is crucial for sharing information with the scientific community, contributing to education, and fostering advancements in various fields, including medicine and pharmacology.
32) Sah:
Shah is a common surname in India, often associated with individuals in various professional fields, including medicine and research. Those bearing this name may contribute to the study and application of traditional medicine, enhancing the understanding of its practices and benefits in contemporary healthcare systems.
33) Food:
Food is any substance consumed to provide nutritional support for the body. In Ayurvedic practices, food choices significantly impact health and well-being. Understanding the role of food in medicinal practices can inform dietary guidelines and enhance treatment approaches for various health conditions, including metabolic syndrome.
34) Life:
Life encompasses the existence of living organisms, characterized by growth, reproduction, and response to stimuli. In healthcare, understanding life's biological processes guides the study of health and diseases, emphasizing the importance of biological research in developing effective treatments and promoting overall well-being.
35) Cinnamomum zeylanicum:
Cinnamomum zeylanicum, or Ceylon cinnamon, is a spice known for its medicinal properties, including anti-inflammatory and anti-diabetic effects. Its active components are studied for potential applications in managing metabolic disorders, underscoring the importance of traditional herbs in modern therapeutic strategies.
36) Berberis aristata:
Berberis aristata, known for its antihyperglycemic properties, is utilized in traditional medicine to manage diabetes and related conditions. Investigating its pharmacological implications contributes to understanding how natural products can offer therapeutic benefits for contemporary health challenges.
37) Piper longum:
Piper longum, commonly known as long pepper, is an Ayurvedic herb renowned for its potential benefits in respiratory and digestive health. It is of particular interest for its bioactive compounds that may support metabolic functions, highlighting its role as a natural remedy in traditional medicine.
38) Plumbago zeylanica:
Plumbago zeylanica, a plant used in traditional medicine, is known for its anti-inflammatory properties. Research into its pharmacological effects can reveal new therapeutic options for conditions like metabolic syndrome, emphasizing the significance of exploring traditional herbs in modern herbal therapies.
39) Saraca asoca:
Saraca asoca, also known as Ashoka tree, is valued in Ayurveda for its restorative properties, particularly for women's health issues. Its pharmacological applications extend to treating various conditions, reinforcing the importance of traditional botanical remedies in health and wellness.
40) Developing:
Developing refers to the process of advancing or evolving concepts, strategies, or products, particularly in the context of drug discovery and healthcare solutions. It encompasses research, innovation, and the integration of knowledge to create effective therapeutic approaches for health management and disease prevention.
41) Ativisa (Ativisha):
Ativisha, or Aconitum heterophyllum, is a renowned medicinal herb in Ayurveda known for its therapeutic properties. Its application in managing various health issues, particularly in traditional medicine practices, highlights the significance of exploring such herbs for modern pharmacological research and drug development.
42) Shilajatu (Silajatu, Shila-jatu):
Silajatu, a natural resin used in Ayurvedic medicine, is known for its rejuvenating qualities and potential health benefits. Its diverse applications, particularly in metabolic and energy-related disorders, underscore the importance of traditional substances in contemporary healthcare strategies and wellness practices.
43) Prameha:
Prameha, in Ayurvedic terminology, refers to a metabolic disorder characterized by symptoms similar to diabetes. Understanding its implications and treatments in traditional medicine provides insights into holistic health management strategies for addressing metabolic syndromes and enhancing overall well-being.
44) Surface:
Surface in biological contexts often refers to the outer layer of cells, tissues, or organisms where interactions with the environment occur. Studying surface characteristics can reveal important information regarding nutrient absorption, microbial interactions, and how therapeutic agents can effectively act upon specific cellular targets.
45) Mishra (Misra):
Mishra is a common Indian surname, often associated with practitioners, researchers, or scholars in the fields of medicine, health, and Ayurveda. Individuals with this name may significantly impact the understanding and application of traditional medicinal practices and their integration into modern health paradigms.
46) Lavana:
Lavana refers to salts, particularly in Ayurvedic medicine, where they are used for their therapeutic properties. Understanding the role of different types of Lavana in health can contribute to dietary practices and treatment protocols for various conditions, reinforcing the significance of traditional remedies.
47) Cancer:
Cancer is a group of diseases characterized by uncontrolled cell growth and division. Advances in research, including pharmacological studies, are fundamental to developing effective treatments and therapies, emphasizing the ongoing need for exploration of natural products derived from traditional medicine as potential cancer therapies.
48) Danti (Dantin, Damti):
Danti, associated with the plant Baliospermum montanum, is recognized for its medicinal uses in traditional practices. Its potential applications in treating health conditions highlight the significance of exploring plants in pharmacological research, particularly in developing therapies for diseases such as diabetes and obesity.
49) Vaca:
Vacha, or Acorus calamus, is an aromatic herb used in Ayurvedic medicine for its cognitive and digestive health benefits. Examining its pharmacological properties provides valuable insights into its potential therapeutic effects, contributing to the broader understanding of traditional medicinal plant applications.
50) Post:
Post in a research context often refers to a phase in a study, such as post-treatment observations or data collection. It is crucial for evaluating the efficacy or effects of an intervention and understanding outcomes in clinical or experimental research settings.
51) Tinospora cordifolia:
Tinospora cordifolia, known as Guduchi, is a significant herb in Ayurveda praised for its immune-modulating and anti-inflammatory properties. Research into its pharmacological effects can lead to potential applications in treating chronic diseases, aligning traditional knowledge with modern scientific discovery.
52) Zingiber officinale:
Zingiber officinale, commonly known as ginger, is widely recognized for its medicinal properties, particularly its anti-inflammatory and digestive benefits. Its integration into both traditional and modern medicine underscores its versatility as a therapeutic agent in managing diverse health conditions.
53) Terminalia chebula:
Terminalia chebula, known as Haritaki, is celebrated in Ayurvedic practices for its various health benefits, including digestive support and antioxidant properties. Its potential applications in contemporary herbal medicine warrant further investigation for therapeutic uses in managing chronic health issues.
54) Curcuma longa:
Curcuma longa, or turmeric, is renowned for its active compound curcumin, recognized for its anti-inflammatory and antioxidant effects. Its incorporation into both traditional and modern medicine highlights its relevance in addressing numerous health concerns, including metabolic syndrome and chronic diseases.
55) Hordeum vulgare:
Hordeum vulgare, commonly known as barley, is a cereal grain valued for its nutritional and health-promoting properties. Its incorporation in dietary practices supports metabolic health, and its applications in traditional medicine provide a basis for further research into its pharmacological benefits.
56) Accumulation (Accumulating, Accumulate):
Accumulation in biological contexts usually refers to the gradual build-up of substances within tissues or cells. Understanding accumulation processes can illuminate factors influencing health or disease states, particularly concerning metabolic disorders and the therapeutic interventions used to manage them.
57) Bhaishajya (Bhaisajya):
Bhaishajya refers to medicine or healing substances in Ayurveda, highlighting its significance as a field dedicated to health and healing. It emphasizes the role of herbal and mineral preparations in treating ailments and promoting well-being through holistic approaches.
58) Hemavati:
Hemavathi is a term that may refer to a specific traditional preparation or herb used in Ayurveda, associated with therapeutic properties. Exploring its significance in traditional practices can provide insights into its applications in modern medicine and health care.
59) Makshika (Maksika):
Makshika, referring to a specific Ayurvedic formulation or substance, is significant within traditional medicine. Understanding its properties and applications can contribute to broader knowledge about herbal and mineral formulations and their roles in health and disease management.
60) Triphala (Tri-phala):
Triphala, a potent Ayurvedic formulation consisting of three fruits, is celebrated for its health benefits, including digestive health, detoxification, and anti-inflammatory properties. Its widespread use underscores the significance of multi-ingredient formulations in promoting overall well-being.
61) Turmeric:
Turmeric, well-known for its active compound curcumin, is prized in both culinary and medicinal applications for its anti-inflammatory and antioxidant properties. Its role in traditional medicine emphasizes the value of natural remedies in contemporary healthcare practices for managing various health conditions.
62) Teaching:
Teaching in a scientific context refers to imparting knowledge about various subjects, including pharmacology, medicine, and alternative therapies. It plays a vital role in education and training to equip future healthcare professionals with the knowledge necessary for effective practice and patient care.
63) Zhejiang:
Zhejiang is a province in China known for its rich culture and traditions, including medicine practices. The understanding of medicinal practices in Zhejiang can provide insights into alternative healing approaches and the integration of traditional medicine with modern scientific research.
64) Govinda (Go-vinda, Govimda):
Govinda is a common name in India, often associated with spiritual or historical significance. In healthcare studies, individuals with this name may engage in research or practices related to Ayurveda and traditional medicine, contributing to the preservation and dissemination of these ancient practices.
65) Pippali (Pippalin):
Pippali, or Piper longum, is a prominent herb in Ayurveda known for its digestive and respiratory benefits. Its chemical constituents are studied for potential therapeutic applications, emphasizing the importance of traditional herbal remedies in modern pharmacological research and holistic health.
66) Gujarat:
Gujarat is a state in India with a rich history of traditional medicine and Ayurvedic practices. Its cultural heritage and diverse flora provide a foundation for studying regional medicinal plants and their applications in conventional and alternative healthcare therapies.
67) Chandra:
Chandra, a name often associated with the moon in Indian mythology, may also refer to individuals contributing to scientific research. Their involvement in pharmacological studies enhances the understanding of traditional medicinal systems and their relevance to modern health practices.
68) Camphor:
Camphor, derived from the wood of the camphor tree, is used in traditional medicine for its aromatic and therapeutic properties. It is known for its potential to alleviate inflammation and pain, making it significant in various herbal formulations.
69) Bhasma (Bhasman):
Bhasma refers to a type of Ayurvedic ash used in herbal formulations, known for its transformative and medicinal properties. Understanding its preparation and application emphasizes the importance of traditional techniques in enhancing the efficacy of treatments within Ayurvedic practices.
70) Kshara (Ksara):
Kshara, in Ayurvedic medicine, refers to alkaline substances derived from ash, used for their therapeutic properties. These natural products are significant in treating various health issues, particularly those related to digestion and inflammation, showcasing the breadth of traditional medicinal knowledge.
71) Shukla (Sukla):
Shukla is a common surname in India, often associated with professionals in various fields, including medicine and research. Individuals with this name may contribute to scientific advancements, particularly in traditional healing systems and their integration into modern medicinal practices.
72) Kamali:
Kamali often refers to individuals within the context of traditional medicine who may engage in researching, teaching, or practicing Ayurveda. Their contributions help preserve ancient knowledge and foster its application in contemporary health and wellness contexts.
73) Arishta (Arista):
Arista generally refers to a family of plants, including medicinal species such as Berberis. These plants often have significant therapeutic properties in traditional medicine systems, underscoring their importance in pharmacological studies aimed at discovering new treatments.
74) Ranjan (Ramjan):
Ranjan is a common Indian name and surname often associated with professionals involved in medicine or research. Individuals with this name may contribute valuable insights into healthcare practices, particularly those surrounding traditional medicine and Ayurvedic principles.
75) Saxena (Sakshena, Saksena):
Saxena is a prevalent surname in India linked to individuals in various professional fields, including medicine and research. Those with this surname may play a role in advancing knowledge and practices in Ayurvedic medicine, bridging traditional practices with contemporary health care.
[Note: The above list is limited to 75. Total glossary definitions available: 156]
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