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Anti-inflammatory activity of root bark and stem bark of Shyonaka

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Journal name: Journal of Ayurveda and Integrative Medicine
Original article title: Anti-inflammatory activity of root bark and stem bark of Shyonaka
The Journal of Ayurveda and Integrative Medicine (JAIM) is an open-access publication promoting collaboration between Ayurveda, traditional medicine, and biomedicine, publishing research on integrative health sciences
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Original source:

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Author:

Krunal Doshi, R Ilanchezhian, Rabinarayan Acharya, B. R. Patel, B. Ravishankar


Journal of Ayurveda and Integrative Medicine:

(A monthly peer-reviewed publication)

Full text available for: Anti-inflammatory activity of root bark and stem bark of Shyonaka

Year: 2012 | Doi: 10.4103/0975-9476.104434

Copyright (license): CC BY-NC-ND 4.0


Download the PDF file of the original publication


Glossary definitions and references:

Scientific and Ayurvedic Glossary list for “Anti-inflammatory activity of root bark and stem bark of Shyonaka�. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.

1) Shyonaka (ÅšyonÄka, ÅšyoṇÄka, SyonÄka):
Shyonaka refers to the root bark of Oroxylum indicum, an important medicinal plant used in Ayurveda. It is known for its therapeutic properties, particularly in treating inflammation and various ailments. The study emphasizes its relevance, comparing its efficacy with the stem bark, which is suggested by the Ayurvedic Pharmacopoeia of India.

2) Animal:
Animal models, particularly Wistar strain albino rats, are essential in the experimental study to evaluate the anti-inflammatory effects of Shyonaka decoctions. The choice of animal ensures controlled conditions, allowing researchers to observe the pharmacological outcomes of the treatments under investigation and contributing to ethical biomedical research.

3) Activity:
Activity in this context relates to the anti-inflammatory actions of the root and stem bark of Shyonaka. The study's purpose is to measure this activity in experimental models, which is key in assessing the therapeutic potential of herbal remedies in treating conditions associated with inflammation, like arthritis.

4) Drug:
The term drug pertains to the kashaya (decoction) derived from Shyonaka, which is administered to test its medicinal properties. Both root and stem bark are evaluated as potential therapeutic agents, exemplifying the importance of natural compounds in developing effective medicines based on traditional knowledge and pharmacology.

5) Water:
Water plays a crucial role as a solvent in preparing the kashaya (decoction) required for the study. It serves as a medium to extract the medicinal constituents from the plant materials, ensuring that the active compounds are available for administration to the animals in the study, highlighting its necessity in herbal preparations.

6) Ayurveda (Ä€yurveda, Ayus-veda):
Ayurveda is a traditional system of medicine originating in India, emphasizing natural remedies and holistic health. The study is anchored in Ayurvedic principles, exploring the efficacy of Shyonaka, an integral component of numerous Ayurvedic formulations, thereby underscoring the relevance of ancient wisdom in modern pharmacological research.

7) India:
India is significant in this context as it is the geographical and cultural origin of Ayurveda and the plant under study, Oroxylum indicum. The biodiversity of India contributes to the richness of its medicinal flora, making it vital for research focused on sustainable utilization and conservation of its medicinal plants.

8) Edema (Oedema):
Edema is a condition characterized by swelling due to excess fluid accumulation, often resulting from inflammation. In the study, carrageenan-induced edema in rats serves as a model to evaluate the anti-inflammatory properties of the decoctions. Thus, it represents a critical endpoint to measure the effectiveness of the treatment.

9) Study (Studying):
The study aims to analyze and compare the anti-inflammatory effects of Shyonaka's root and stem barks. Through rigorous experimental design and methodology, it seeks to generate data that can substantiate traditional claims regarding the herb's therapeutic actions, contributing to evidence-based validation in herbal medicine.

10) Oroxylum indicum:
Oroxylum indicum is the scientific name of the tree from which Shyonaka is derived. Recognized for its various medicinal properties, this plant is the focus of the study. Understanding its phytochemistry and biological effects provides insights into its therapeutic potential and helps in conservation efforts given its vulnerable status.

11) Kashaya (KÄá¹£Äya, KÄÅ›aya, KÄsÄya, Kaá¹£Äya, KaÅ›Äya, KÄsaya, Kaá¹£ÄyÄ, KasÄya, Kasaya):
Kashaya refers to a decoction made from the root or stem bark of Shyonaka in this study. By preparing kashaya, researchers can extract the therapeutic compounds effectively. The decoction's preparation and application are essential for assessing its pharmacological effects and ensuring that the experimental results are reliable and valid.

12) Disease:
The term disease encompasses various health conditions that the kashaya (decoction) of Shyonaka aims to address, particularly those linked to inflammation, such as rheumatoid arthritis and tuberculosis. Evaluating the anti-inflammatory activity of the decoction can reveal its potential therapeutic applications in managing these and other related diseases.

13) Powder:
Powder refers to the powdered form of Shyonaka bark used in Ayurvedic practices. It signifies one of the various dosage forms used in medicine, demonstrating the versatility of the plant in the preparation of herbal medicinal products. This underscores the importance of different forms in traditional and contemporary therapies.

14) Rheumatoid arthritis:
Rheumatoid arthritis (RA) is a chronic inflammatory disorder that the study aims to address through the anti-inflammatory properties of Shyonaka decoction. By investigating its effects, the research can highlight the potential of the plant as a complementary approach in managing this debilitating condition prevalent worldwide.

15) Pharmacology:
Pharmacology is the scientific discipline that examines drug actions and interactions. The study integrates principles of pharmacology by evaluating the anti-inflammatory effects of Shyonaka, thereby bridging traditional Ayurvedic knowledge with modern scientific research methods to validate and explore the therapeutic potential of herbal compounds.

16) Tuberculosis:
Tuberculosis (TB) is a serious infectious disease that has been historically treated with herbal remedies, including formulations containing Shyonaka. The study's exploration of anti-inflammatory activity could provide valuable insights into adjunct therapies for TB, emphasizing the relevance of traditional treatments in contemporary disease management.

17) Inflammation:
Inflammation is a biological response that the study aims to mitigate using Shyonaka's decoctions. Understanding the influence of the root and stem bark on inflammation can lead to broader implications for treating inflammatory diseases, enhancing the therapeutic repertoire available to practitioners of traditional and modern medicine alike.

18) Calculation:
Calculation is important for determining appropriate dosing for animal studies based on their body weight and surface area. This assures that the experimental treatments are both safe and effective, reflecting standards of care and accuracy necessary in pharmacological studies to ensure the validity of findings.

19) Dravyaguna (Dravyaguṇa, Dravya-guna):
Dravyaguna is a branch of Ayurveda focused on the study of medicinal properties of herbs, including their pharmacological actions. It plays a critical role in understanding the therapeutic uses of Shyonaka within Ayurvedic medicine, supporting the study's goal of empirical validation of ancient practices through modern research methodologies.

20) Fixation:
Fixation in this context refers to establishing dosing protocols for the animal trials. Proper fixation ensures consistency and reliability in research methodologies, thereby enhancing the credibility of results and allowing for appropriate comparisons of the anti-inflammatory effects of the decoctions being tested.

21) Gujarat:
Gujarat is the state in India where the Shyonaka samples were collected. Its biodiversity contributes to the availability of numerous medicinal plants, including Oroxylum indicum, making it significant for research focused on traditional medicine and sustainable practices in herbal resource management within the region.

22) Amavata (Ä€mavÄta, Ama-vata):
Amavata is an Ayurvedic term closely related to rheumatoid arthritis, highlighting the relevance of Shyonaka in treating such conditions. The study indicates that exploring Shyonaka's anti-inflammatory properties could potentially yield insights and therapeutic benefits for patients suffering from this chronic inflammatory disease.

23) Leprosy:
Leprosy is a chronic infectious disease historically treated with various traditional remedies, including those containing Shyonaka. The study indirectly supports the importance of plant-based treatments in addressing such diseases through an understanding of the biological activity of compounds derived from Oroxylum indicum.

24) Surface:
Surface refers in this context to the calculation of doses based on the body surface area of animals in the experimental study. This method ensures that the dosages are appropriately scaled, enhancing the reliability and comparability of the experimental results drawn from the administered treatments.

25) Shotha (Åšotha, Åšoá¹­ha, Soá¹­hÄ):
Sotha, meaning inflammation in Ayurveda, is a key focus of the study exploring the efficacy of Shyonaka. By studying its effects on sotha, researchers aim to substantiate traditional claims about the plant and contribute valuable data to the ongoing exploration of herbal remedies for inflammatory conditions.

26) Table:
Table refers to the reference table used for calculating doses based on body surface area in the study. This tool is essential for determining accurate and standardized dosages for animal experiments, aiding in the safety and effectiveness of the pharmacological evaluation.

27) House:
House refers to the specific setting, such as the animal house associated with the pharmacology laboratory, where the experimental animals are kept. The environment plays a crucial role in the outcomes of the study by ensuring proper care and conditions necessary for conducting ethical animal research.

28) Dang (ḌÄá¹…g):
Dang is the district in Gujarat where Shyonaka samples were collected for the study. This regional significance highlights the specific ecological settings that contribute to the access and study of this vulnerable species, underscoring the importance of local biodiversity in traditional medicine and pharmaceutical research.

29) Tree:
Tree, in reference to Oroxylum indicum, indicates the source of Shyonaka. Understanding the ecological roles, conservation status, and traditional uses of this tree species emphasizes the connection between natural resources and their medicinal applications, prompting the necessity of sustainable practices in herbal medicine.

30) Hind (Hiṇá¸):
Hind refers to the hind limb of the rats used in the edema study. Inducing edema in this specific area is a crucial aspect of the experimental design for measuring the anti-inflammatory effects of the decotion, underscoring the importance of anatomical considerations in pharmacological studies.

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Discover the significance of concepts within the article: �Anti-inflammatory activity of root bark and stem bark of Shyonaka�. Further sources in the context of Science might help you critically compare this page with similair documents:

Decoction preparation, Pharmaceutical method, Statistical analysis, Ayurvedic formulation, Anti-inflammatory activity, Observational study, Experimental model, Ayurvedic Pharmacopoeia of India, Anti-inflammatory formulation, Wistar strain albino rats, Dashamoola, Carrageenan, Vulnerable medicinal plant, Natural Population.

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