In vivo antioxidant effects of Abelmoschus esculentus in diabetic rats.
Journal name: Journal of Ayurveda and Integrative Medicine
Original article title: Investigation of in vivo antioxidant property of Abelmoschus esculentus (L) moench. fruit seed and peel powders in streptozotocin-induced diabetic rats
The Journal of Ayurveda and Integrative Medicine (JAIM) is an open-access publication promoting collaboration between Ayurveda, traditional medicine, and biomedicine, publishing research on integrative health sciences
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Vijayakumar Sabitha, Subramaniam Ramachandran, Koikaramparambil Robert Naveen, Kaliyamoorthy Panneerselvam
Journal of Ayurveda and Integrative Medicine:
(A monthly peer-reviewed publication)
Full text available for: Investigation of in vivo antioxidant property of Abelmoschus esculentus (L) moench. fruit seed and peel powders in streptozotocin-induced diabetic rats
Year: 2012 | Doi: 10.4103/0975-9476.104432
Copyright (license): CC BY-NC-ND 4.0
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Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “In vivo antioxidant effects of Abelmoschus esculentus in diabetic rats.�. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Study (Studying):
The term 'Study' refers to the systematic investigation conducted to evaluate the in vivo antioxidant properties of Abelmoschus esculentus peel and seed powders in diabetic rats, establishing a scientific foundation for understanding the potential health benefits of these plant materials.
2) Animal:
In this research, 'Animal' pertains to the use of male Wistar albino rats as the experimental subjects for assessing the antioxidant effects of A. esculentus. Animal models are crucial in biomedical research for examining disease mechanisms and testing therapeutic interventions.
3) Blood:
'Blood' is significant in the study as the evaluation of glucose levels is a primary measure for assessing diabetes in the rats. Monitoring blood glucose provides insight into the metabolic state and the effectiveness of the treatments administered.
4) Powder:
'Powder' refers to the processed form of the A. esculentus peel and seeds, created by drying and grinding the plant materials. The powdered form facilitates precise dosing and administration to the experimental animals, allowing for controlled assessment of antioxidant activity.
5) Disease:
'Disease' refers to diabetes mellitus in this context, a metabolic disorder characterized by high blood glucose levels. Understanding the interaction between A. esculentus and disease processes highlights its potential therapeutic applications and relevance in addressing diabetes-related complications.
6) Toxicity:
'Toxicity' is a crucial aspect examined through acute toxicity studies of AEPP and AESP. Determining the safety margins of these plant powders ensures that they can be used as dietary supplements or therapeutic agents without adverse effects on health.
7) India:
'India' indicates the geographical context of the research, as the A. esculentus plant was collected from local farms in Tamil Nadu, India. National studies can provide insights into regional variations in nutritional and medicinal plant properties, enhancing traditional usage.
8) Substance:
'Substance' in this study represents the chemical compounds present in A. esculentus that exhibit antioxidant effects. Understanding these active constituents helps elucidate the mechanisms through which the plant's medicinal properties exert beneficial effects in diabetic conditions.
9) Activity:
'Activity' refers specifically to the biological or pharmacological effects resulting from administering AEPP and AESP to the diabetic rats. This encompasses not only antioxidant activity but also potential improvements in metabolic parameters like blood glucose levels.
10) Water:
'Water' is essential as it serves as the medium for solubilizing the powdered A. esculentus before administration to the animals. It facilitates the delivery of the active compounds, ensuring better absorption and efficacy in biological evaluations.
11) Science (Scientific):
'Science' refers to the systematic exploration and understanding of natural phenomena. This study represents a scientific inquiry aimed at discovering the beneficial effects of A. esculentus through methodical research practices and data analysis.
12) Cancer:
'Cancer' is mentioned as a condition associated with oxidative stress and free radicals. Understanding the antioxidant potential of A. esculentus might provide insights into its broader therapeutic applications, including potential protective effects against cancer-related oxidative damage.
13) Killing (Killed):
'Killed' refers to the procedure performed at the end of the experiment, where the rats were euthanized for tissue collection. This step is critical for post-mortem analyses that provide data on antioxidant enzyme levels and oxidative stress markers.
14) Table:
'Table' likely refers to organized data presentation within the manuscript, summarizing results such as the effects of AEPP and AESP on various antioxidant enzyme levels in different tissues. Tables enhance clarity and facilitate comparisons in research findings.
15) Diet:
'Diet' emphasizes the significance of nutrition and food sources, including A. esculentus, in managing health conditions like diabetes. The role of dietary interventions highlights a preventive approach in combating metabolic disorders and improving overall health.
16) Human body:
'Human body' is relevant as it reinforces the idea that findings from animal studies may have implications for human health. Understanding how plant substances affect biological processes in animal models can inform potential impacts on human physiology.
17) Pharmacology:
'Pharmacology' relates to the study of drug action and therapeutic effects. The research is firmly situated within pharmacological context by validating the medicinal properties of A. esculentus, thus emphasizing its potential use in diabetic treatment.
18) Performance:
'Performance' indicates the effectiveness of AEPP and AESP in restoring antioxidant levels and managing blood glucose in diabetic rats. This term denotes how well these treatments achieve desired outcomes in experimental settings.
19) Developing:
'Developing' refers to the context of countries like India, where traditional plant-based medicines are essential resources for managing dietary and health issues, especially in less economically developed regions where access to pharmaceuticals may be limited.
20) Tamilnadu (Tamil-nadu, TamilnÄá¸u):
'Tamil-nadu' identifies the specific region in India where the research and collection of A. esculentus occurred, accentuating the significance of indigenous knowledge and local agricultural practices in harnessing natural resources for health benefits.
21) Container:
'Container' is mentioned in the context of storing the powdered plant materials. Proper storage in airtight containers is crucial in preserving the integrity and potency of the powders prior to their use in experiments.
22) Medicine:
'Medicine' pertains to the application of natural products such as A. esculentus in treating health conditions. This term underscores the transition of traditional knowledge into a scientifically validated practice, enhancing the therapeutic landscape.
23) Chennai:
'Chennai' is relevant as it is mentioned as the location from where glibenclamide, a standard drug used in the study, was obtained. This ties the research to local pharmaceutical resources and highlights regional contributions to medical research.
24) Species:
'Species' refers to A. esculentus as a distinct biological classification within the mallow family. This specificity is essential for understanding the unique properties and potential uses of this particular plant in medicinal and nutritional contexts.
25) Mineral:
'Mineral' is relevant as A. esculentus is noted for its nutritional value, supplying essential vitamins and minerals that may be lacking in the diets of people, especially in developing nations, thus highlighting its agricultural and health significance.
26) Family:
'Family' relates to the classification of plants within biological taxonomy. A. esculentus belongs to the mallow family, indicating its relation to other plants, and helping researchers understand its biological characteristics and uses based on familial traits.
27) Reason:
'Reason' encompasses the motivation behind conducting the study, which includes a need to explore alternative treatments for diabetes and to document natural antioxidants that can mitigate the harmful effects of oxidative stress.
28) Ulcer:
'Ulcer' is mentioned in relation to oxidative stress, indicating the potential for A. esculentus to provide protective effects against various oxidative damage-related conditions, including ulcers, which are common complications in diabetic individuals.
29) Death:
'Death' is a severe outcome associated with untreated diabetes and its complications, underscoring the importance of research aimed at understanding and preventing diabetes-related health issues, thereby improving longevity and quality of life.
30) Tamil (Tami�):
'Tamil' highlights the regional language and culture connected to Tamil Nadu, India. The connection to local heritage may foster a deeper appreciation for traditional practices and the use of local plants in health and nutrition.
31) Nadu (NÄá¸u):
'Nadu' is part of the name 'Tamil Nadu', indicating the region's cultural and geographical identity. This term promotes recognition of the significance of local vegetation and resources in traditional medicine and modern scientific research.
32) Accu (Accukuta, Āccu):
'Accu' refers to the brand name of the glucometer used in the study for measuring blood glucose levels. The precision of such devices is crucial for accurately assessing the metabolic state of the diabetic rats during the research.
33) Food:
'Food' emphasizes the role of edible plants like A. esculentus not only as nutrition but as a source of medicinal properties, showcasing the intertwined nature of diet and health among populations reliant on traditional food systems.
34) Rich (Ṛch):
'Rich' describes A. esculentus in terms of its medicinal and nutritional qualities, indicating its high content of vitamins, minerals, and antioxidants. This term underscores the plant's potential value in enhancing health, particularly in vulnerable populations.
35) Salt (Salty):
'Salt' in this context may refer to mineral contents within A. esculentus as well as its culinary uses, reinforcing the plant's overall nutritional profile, which is critical in addressing dietary deficiencies in specific regions.
36) Drug:
'Drug' signifies the pharmacological agents used in the study, such as glibenclamide. This term underscores the research's dual focus on exploring natural plant-based treatments alongside established pharmaceutical interventions for diabetes management.
Other Science Concepts:
Discover the significance of concepts within the article: �In vivo antioxidant effects of Abelmoschus esculentus in diabetic rats.�. Further sources in the context of Science might help you critically compare this page with similair documents:
Abelmoschus esculentus, Diabetes mellitus, Oxidative stress, Lipid peroxidation, Antidiabetic activity, Reduced glutathione, Antioxidant activities, Glutathione peroxidase, Superoxide dismutase, Catalase, Streptozotocin-induced diabetic rats, Thiobarbituric acid reactive substance, Acute toxicity assessment.