Study comparing withdrawal symptoms of Madatyaya with Punarnavadi Ghrita.
Journal name: Ayushdhara
Original article title: A comparative clinical study on withdrawal symptoms of madatyaya with punarnavadi ghrita
AYUSHDHARA is an international peer-reviewed journal. It focuses on research in Ayurveda, Yoga, Unani, Siddha, Homeopathy, Allopathy, and Pharmaceutical Sciences.
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*Chawla Kumar Satbir
Lecturer, Dept. of Agadtantra, Glocal college of Ayurvedic Medical Sciences and Research Center, Saharanpur, Uttar Pradesh
Priyanka Dr
Lecturer, Stri Roga and Prasuti tantra Department, Chaudhary Devi Lal college of Ayurveda, Yamuna Nagar, Haryana
Dhiman Sonia
Lecturer, Dravyaguna Department, Ch. Devi Lal College of Ayurveda, Haryana
Kumar Ajay
Ayurvedic Medical officer, Ayush Department, Government of Haryana
Ayushdhara:
(A peer-reviewed, bi-monthly open-access journal)
Full text available for: A comparative clinical study on withdrawal symptoms of madatyaya with punarnavadi ghrita
Year: 2016
Copyright (license): CC BY-NC-SA 4.0
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Summary of article contents:
Introduction
The clinical study presented focuses on the management of withdrawal symptoms associated with Madatyaya, which is interpreted within Ayurvedic texts as a condition resulting from excessive alcohol consumption, akin to modern alcoholism. With the rise in alcohol addiction among the youth and middle-aged individuals, the detrimental social and economic impacts necessitate effective interventions. This study evaluated two treatment approaches: one using the conventional medicine provided by a drug de-addiction center and the other employing Punarnavadi Ghritta, an Ayurvedic formulation. The objective was to assess the clinical efficacy of these two methodologies in managing withdrawal symptoms over a period of 30 days.
Clinical Efficacy of Punarnavadi Ghritta
One significant finding of the study is the comparative efficacy of Punarnavadi Ghritta over conventional treatment in addressing objective clinical parameters. While both treatments were effective in their own right, Punarnavadi Ghritta exhibited superior results in laboratory evaluations, including improvements in liver function tests and blood parameters mentioned like TLC (Total Leukocyte Count) and ESR (Erythrocyte Sedimentation Rate). The Ayurvedic formulation incorporates ingredients known for their rejuvenating and detoxifying properties, promoting overall vitality and aiding in the alleviation of withdrawal symptoms like excruciating pain and fatigue, which are characteristic of Madatyaya.
Importance of Subjective Parameter Evaluation
Another noteworthy observation was the performance of conventional treatment concerning subjective parameters associated with withdrawal symptoms. The standard medication method showed statistically significant effectiveness in reducing symptoms experienced by patients, such as burning sensations and discomfort in the chest. This highlights the role of conventional medicine in managing immediate discomforts linked with withdrawal, demonstrating that while it may not be as effective in addressing laboratory findings, it can provide needed relief for acute symptoms reported by patients. This reveals the dichotomy between subjective experience and objective physiological outcomes in treatment.
Conclusion
In conclusion, the study underscores the complexities involved in treating Madatyaya and similar alcohol-related disorders, blending traditional Ayurvedic practices with modern therapeutic approaches. Punarnavadi Ghritta emerges as a promising candidate for enhancing laboratory-valued parameters in patients, while conventional medications effectively mitigate subjective discomfort associated with withdrawal. The findings suggest that an integrative approach, combining both paradigms, may provide the most holistic care for individuals grappling with withdrawal from alcohol, fostering better health outcomes and enhancing their overall well-being. Thus, the dual application of these methods could be an essential component in the larger context of alcohol addiction recovery strategies.
FAQ section (important questions/answers):
What is Madatyaya and its relation to alcoholism?
Madatyaya is a condition caused by excessive use of Madya, correlating with alcoholism. It results in withdrawal symptoms similar to those experienced by chronic alcoholics, impacting physical and mental health.
What were the treatment groups in the study?
The study comprised two groups: Group-A received modern medicine from a Drug De-addiction center, while Group-B was treated with Punarnavadi Ghritta for managing withdrawal symptoms over 30 days.
What were the main findings of the study?
Group-B, treated with Punarnavadi Ghritta, showed significant improvements in laboratory parameters like TLC and liver function tests compared to Group-A, highlighting its efficacy in managing withdrawal symptoms of Madatyaya.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “Study comparing withdrawal symptoms of Madatyaya with Punarnavadi Ghrita.�. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Madatyaya (Mada-atyaya):
Madatyaya refers to the disease caused by the excessive and improper use of Madya (alcohol). It results in various physical and mental symptoms which are detailed in Ayurvedic texts. These symptoms include pain, unconsciousness, and various discomforts associated with substance dependence.
2) Drug:
The term drug in this context refers to the medicinal substances used to treat withdrawal symptoms of Madatyaya. Specifically, the study compares the efficacy of modern de-addiction center medicine and Punarnavadi Ghrita, an Ayurvedic preparation.
3) Punarnavadi:
Punarnavadi is part of the term Punarnavadi Ghrita, an Ayurvedic medicinal preparation used to treat symptoms of Madatyaya. It comprises herbs and ingredients like Punarnava, Yashtimadhu, Go-dugdha, and Go-ghritta known for their therapeutic properties.
4) Madya:
Madya in Ayurveda refers to alcoholic beverages. It is described as capable of causing both therapeutic and deleterious effects, depending on the manner of its use. Excessive and improper use leads to the condition known as Madatyaya.
5) Alcoholism:
Alcoholism is a modern term corresponding to the condition described in Ayurveda as Madatyaya. It involves dependency on alcohol with symptoms manifesting upon withdrawal, including both physiological and psychological effects.
6) Medicine:
Medicine in this study refers to the therapeutic agents used to treat alcohol withdrawal symptoms. Two types were compared: modern medicine provided by drug de-addiction centers, and Punarnavadi Ghrita, an Ayurvedic preparation.
7) Disease:
The disease discussed here is Madatyaya, caused by the excessive intake of alcohol (Madya), characterized by a broad set of withdrawal symptoms. The study aims to manage the withdrawal effects associated with this disease.
8) Madhura:
Madhura is one of the six tastes in Ayurveda. Ingredients like Go-ghritta (ghee) and Yashtimadhu (liquorice) have a Madhura (sweet) taste, which is typically nourishing and considered balancing for Pitta and Vata doshas.
9) Aruci:
Aruchi in this context refers to the symptom of tastelessness or anorexia seen in patients with Madatyaya. It is one of the withdrawal symptoms that the study aimed to address using therapeutic agents.
10) Ayurveda (Ayus-veda):
Ayurveda is the ancient Indian system of medicine, which forms the basis of the treatment methods evaluated in the study. It emphasizes a holistic approach to health and the balance of body doshas (Vata, Pitta, Kapha).
11) Rasayana (Rasa-ayana):
Rasayana refers to rejuvenative treatments in Ayurveda. Punarnavadi Ghrita, the study’s Ayurvedic medicine, acts as a Rasayana, helping in nourishing the body, enhancing immunity, and counteracting the withdrawal symptoms of alcohol dependency.
12) Pralapa:
Pralapa means delirium or irrelevant speech, a symptom observed in Madatyaya. The effectiveness of treatments in reducing Pralapa was one of the parameters evaluated in the clinical study.
13) Chardi:
Chardi refers to vomiting, a symptom associated with Madatyaya. The study measures the efficacy of treatments like Punarnavadi Ghrita in reducing the occurrence of Chardi in patients undergoing alcohol withdrawal.
14) Pitta:
Pitta is one of the three primary doshas in Ayurveda, representing elements of fire and water. Imbalance in Pitta due to alcohol intake is discussed in the context of Madatyaya, requiring specific treatments to restore balance.
15) Kumar:
Kumar likely references one of the authors of the study, specifically Chawla Kumar Satbir, who conducted the comparative clinical study on Madatyaya withdrawal symptoms using Punarnavadi Ghrita.
16) Atisara:
Atisara translates to diarrhea. It is another symptom observed in patients with Madatyaya and one of the clinical parameters measured to assess the effectiveness of the treatments mentioned in the study.
17) Trishna (Trsna):
Trishna signifies intense or incessant thirst, a prominent withdrawal symptom of Madatyaya. The study assesses treatments for their effectiveness in alleviating Trishna among other observed symptoms.
18) Samaka (Shamaka):
Shamaka refers to substances that pacify or balance the doshas. Ingredients in Punarnavadi Ghrita are described as Tridosha Shamaka, meaning they help in balancing all three doshas (Vata, Pitta, and Kapha).
19) Bhrama:
Bhrama refers to giddiness or vertigo, a symptom of Madatyaya. Evaluating the effectiveness of the therapies in relieving Bhrama was part of the study on alcohol withdrawal symptoms.
20) Thirst:
Thirst, related to Trishna, is a significant symptom in Madatyaya withdrawal. Patients might experience unrelieved thirst even after drinking water. This symptom was evaluated to determine the effectiveness of Punarnavadi Ghrita and modern medicines.
21) Rasa (Rasha):
Rasa can refer to taste in the context of Ayurveda. The Rasa of a substance informs its therapeutic action, with Madhura (sweet) Rasa in Punarnavadi Ghrita playing a role in nourishing and maintaining dosha balance.
22) Guna:
Guna refers to the qualities or properties of substances in Ayurveda. Each medicinal ingredient in Punarnavadi Ghrita has specific Gunas that contribute to their therapeutic actions in treating withdrawal symptoms of Madatyaya.
23) Pain:
Pain, correlated with ‘Shareera Dukham� in Madatyaya, is a common withdrawal symptom. The study aimed to evaluate the extent to which different treatments could alleviate such pain in patients detoxifying from alcohol.
24) Discussion:
Discussion, typically a section in research articles, analyzes the findings. In this study, the discussion likely explores the comparative outcomes of using Punarnavadi Ghrita vs. modern medicine for treating Madatyaya symptoms.
25) Punarnava (Punar-nava):
Punarnava is an herb known for its therapeutic properties, including anti-inflammatory and detoxifying effects. It is a key ingredient in Punarnavadi Ghrita, used in the study to treat withdrawal symptoms of Madatyaya.
26) Lakshana (Laksana):
Lakshana refers to symptoms or signs. The study evaluates the ‘Samanya Lakshanas� (general symptoms) of Madatyaya, drawing parallels with symptoms of alcohol withdrawal to assess treatment efficacy.
27) Sweating (Sweat):
Sweating, or Sweda, is a symptom associated with alcohol withdrawal (Madatyaya). The clinical trial assesses how effectively treatments like Punarnavadi Ghrita and modern medicines reduce excessive sweating in patients.
28) Ghrita (Ghrta):
Ghrita means ghee (clarified butter), used as a base for many Ayurvedic formulations. Punarnavadi Ghrita, a medicated ghee, was used in the study to treat withdrawal symptoms of Madatyaya owing to its therapeutic properties.
29) Daha:
Daha translates to burning sensation. It is one of the symptoms evaluated in the study on Madatyaya withdrawal, observing the effects of treatments like Punarnavadi Ghrita in alleviating this discomfort.
30) Godugdha:
Go-dugdha means cow's milk. It is one of the ingredients in Punarnavadi Ghrita, chosen for its nourishing and pacifying properties, contributing to the treatment of withdrawal symptoms caused by Madatyaya.
31) Vomiting:
Vomiting or Chardi is a common withdrawal symptom of Madatyaya. The study assesses the efficacy of Punarnavadi Ghrita and modern medicine in reducing the frequency and severity of vomiting in patients.
32) Samanya:
Samanya refers to general or common, as in Samanya Lakshanas (general symptoms) of Madatyaya. The study looks at these common symptoms to evaluate the effectiveness of different treatments.
33) Snigdha:
Snigdha is a property describing oiliness or unctuousness in Ayurveda. Ingredients like Go-ghritta (ghee) are Snigdha and are used to balance Vata and Pitta doshas in the treatment of Madatyaya symptoms.
34) Dugdha:
Dugdha refers to milk, specifically Go-dugdha (cow's milk), an ingredient in Punarnavadi Ghrita. Milk is considered nourishing and pacifying for Vata and Pitta doshas, aiding in symptom relief.
35) Medhya:
Medhya refers to substances that enhance cognitive functions. Ingredients like Yashtimadhu in Punarnavadi Ghrita have Medhya properties, aiding in mental clarity and stability in patients with withdrawal symptoms.
36) Vyadhin (Vyadhi):
Vyadhi means disease or ailment. In the context of Madatyaya, it refers specifically to the condition resulting from chronic alcohol use and its associated withdrawal symptoms addressed by the study.
37) Dosha (Dosa):
Dosha refers to the three fundamental bodily humors (Vata, Pitta, Kapha) in Ayurveda. An imbalance in these doshas is responsible for various diseases, including Madatyaya, necessitating treatments that restore dosha balance.
38) Kapha:
Kapha is one of the three doshas, representing elements of water and earth. The study discusses its imbalance in the context of Madatyaya, where Punarnavadi Ghrita aims to balance Kapha among other doshas.
39) Laghu:
Laghu is a quality meaning lightness. It is used to describe substances or diets that are easy to digest and balance Kapha dosha. The patient’s constitution and dietary habits are considered in treating Madatyaya.
40) Guru:
Guru refers to heaviness, a quality in Ayurvedic substances. Medicines or diets with Guru quality nourish and stabilize, often recommended to balance Vata dosha, an aspect considered in treating Madatyaya.
41) Food:
Food plays a crucial role in managing Madatyaya, where improper dietary habits can worsen symptoms. The study evaluates how dietary adjustments and therapeutic diets assist in alleviating alcohol withdrawal symptoms.
42) Horripilation:
Horripilation, or Sphuranam, is the sensation of hair standing on end. It is one of the withdrawal symptoms in Madatyaya that the clinical study measures to assess the impact of treatments like Punarnavadi Ghrita.
43) Yashtimadhu (Yastimadhu, Yashti-madhu):
Yashtimadhu, or licorice, is an Ayurvedic herb included in Punarnavadi Ghrita for its therapeutic properties. It helps balance doshas and alleviates symptoms like inflammation and mental strain associated with Madatyaya.
44) Vatapitta (Vata-pitta):
Vata-pitta refers to the combination of the Vata and Pitta doshas. Many symptoms of Madatyaya are attributed to the imbalance of these doshas, which the study aims to address through various treatments.
45) Trembling (Tremble, Trembled):
Trembling or Shareera Kampa is a symptom associated with Madatyaya resulting from nervous excitability during withdrawal. The study assesses how therapies, including Punarnavadi Ghrita, alleviate such symptoms.
46) Stiffness:
Stiffness is reflected in the symptom called Trikagraha, indicating rigidity in joints, commonly seen in Madatyaya. The study measures treatment effectiveness in reducing muscular and joint stiffness during alcohol withdrawal.
47) Tridosha (Tridosa, Tri-dosha):
Tridosha encompasses the three doshas - Vata, Pitta, and Kapha. Health in Ayurveda depends on the balance among these doshas, and treatments aim to address their imbalance in conditions like Madatyaya.
48) Sammoha:
Sammoha means unconsciousness or confusion, a severe symptom of Madatyaya. The study monitors the effectiveness of interventions in reducing episodes of Sammoha experienced during withdrawal.
49) Atibala:
[see source text or glossary: Atibala]
50) Prakopa:
Prakopa refers to the aggravation of doshas. In Madatyaya, alcohol consumption causes the Prakopa of Vata and Pitta doshas, leading to various symptoms which the study's treatments aim to pacify.
51) Jrimbha (Jrmbha):
Jrimbha stands for yawning, specifically severe yawning as a withdrawal symptom of Madatyaya. The treatment efficacy of Punarnavadi Ghrita and modern medicine in reducing Jrimbha is also evaluated.
52) Pratata:
Pratata refers to ceaseless or intense, often used in describing symptoms like Pratata Trishna (incessant thirst) in Madatyaya, a condition the study aims to treat.
53) Dravya:
Dravya means substance or matter in Ayurveda. Each treatment involves selecting specific Dravyas with properties to counteract the imbalanced doshas and symptoms of Madatyaya.
54) Vedana:
Vedana means pain, an overarching symptom in Madatyaya. Treatments in the study, including Punarnavadi Ghrita, are evaluated for their efficacy in alleviating different types of pain experienced during withdrawal.
55) Ruksha (Ruksa):
Ruksha means dryness, one of the qualities that can lead to dosha imbalance. Alcohol dries out bodily tissues, and treatments aim to counter this with unctuous remedies like Ghrita (clarified butter).
56) Dushya (Dusya):
Dushya refers to bodily elements that become affected in disease. In Madatyaya, the Dushyas are Rasa and Rakta (blood), necessitating treatments that purify and balance these elements.
57) Shrama (Srama):
Shrama means fatigue, a common symptom seen in Madatyaya. The effectiveness of therapies in reducing Shrama is an important measure in the clinical study's evaluation of treatments for alcohol withdrawal.
58) Vipaka:
Vipaka refers to the post-digestive effect of a substance. The Vipaka of therapeutic agents, like those in Punarnavadi Ghrita, influences their dosha-balancing capacity in treating Madatyaya.
59) Srotas (Shrotas):
Srotas are bodily channels or pathways involved in the function of tissues and organs. Madatyaya involves Srotodushti (channel obstruction), which treatments like Punarnavadi Ghrita aim to rectify.
60) Family:
Family context is crucial in treating Madatyaya, as support systems and counselling at family levels can significantly impact the effectiveness of the treatment, as indicated in the study.
61) Nausea:
Nausea, or Hrilasa, is commonly observed in Madatyaya. The study measures how well treatments like Punarnavadi Ghrita reduce nausea along with other withdrawal symptoms.
62) Shiras (Siras, Siro, Shirash):
Shirah refers to the head. Pain in the head (Shirah Vedana) is a notable symptom of Madatyaya, which the study evaluates treatments for, aiming to reduce this type of discomfort.
63) Rakta:
Rakta means blood, one of the bodily elements or Dhatus affected in Madatyaya. Treatments often involve purifying and balancing Rakta to alleviate symptoms and restore health.
64) Hikka:
Hikka means hiccup. It is listed as a symptom in the withdrawal manifestations of Madatyaya. The study evaluates the effectiveness of treatments like Punarnavadi Ghrita in alleviating this symptom.
65) Dhatu:
Dhatu refers to body tissues in Ayurveda. Alcohol abuse leads to the depletion ('Kshaya') of Dhatus, and treatments aim to regenerate and strengthen these tissues, especially with Rasayana therapies.
66) Kampa:
Kampa signifies trembling of the body, a symptom of Madatyaya discussed in the study. Treatment effectiveness in reducing Kampa is part of the clinical evaluation of therapies.
67) Varga:
Varga means group or classification, often used in Ayurvedic texts. For example, Yashtimadhu belongs to the Chedanadi Varga, indicating its therapeutic properties relevant to Madatyaya treatment.
68) India:
India is the country where this study took place, specifically focusing on Ayurveda - the traditional Indian system of medicine for treating conditions like Madatyaya.
69) Ayus (Ayush):
Ayush pertains to the Indian system of traditional medicine (Ayurveda, Yoga, Unani, Siddha, and Homeopathy). The journal AYUSHDHARA publishes research in these fields, including studies like this one on Madatyaya.
70) Fever:
Fever, or Jvarah, characterized by fluctuating temperatures (Sheetoshna Lakshana), is a symptom associated with Madatyaya. The study assessed treatments for their ability to manage and reduce fever in patients.
71) Blood:
Blood tests (Hb, TLC, DLC, ESR, LFT etc.) were performed before and after the trial to assess the effectiveness of treatments like Punarnavadi Ghrita in improving blood parameters in patients with Madatyaya.
72) Devi:
Devi likely references Chaudhary Devi Lal College of Ayurveda, an institution involved in the study. Priyanka and Sonia Dhiman, co-authors, are from this college, contributing their expertise to the research.
73) Vata:
Vata is one of the three doshas, representing air and ether elements. In Madatyaya, Vata imbalance contributes to many symptoms, hence treatments aimed to balance Vata are critical in the study.
74) Kasa (Kasha):
Kasa means cough, a withdrawal symptom of Madatyaya. The study evaluated the effectiveness of treatment methods like Punarnavadi Ghrita in alleviating Kasa among other symptoms in patients.
75) Burning sensation:
Burning sensation, or Daha, is one of the withdrawal symptoms in Madatyaya. The effectiveness of the treatments like Punarnavadi Ghrita in providing relief from this distressing symptom is evaluated in the study.
[Note: The above list is limited to 75. Total glossary definitions available: 137]
Other Science Concepts:
Discover the significance of concepts within the article: �Study comparing withdrawal symptoms of Madatyaya with Punarnavadi Ghrita.�. Further sources in the context of Science might help you critically compare this page with similair documents:
Dosha, Ayurveda, Rasayana, Madatyaya, Alcoholism, Statistical analysis, Inclusion criteria, Exclusion criteria, Comparative clinical study, Clinical efficacy, Laboratory investigation, Significant improvement, Subjective parameter, Objective parameter, Tridoshaja vyadhi, Withdrawal symptoms, Drug de-addiction centre.