Effect of Drakshavaleha in cyclophosphamide induced weight loss and reduction in crown-rump length in developing mice embryo
Journal name: AYU (Journal of Research in Ayurveda)
Original article title: Effect of Drakshavaleha in cyclophosphamide induced weight loss and reduction in crown-rump length in developing mice embryo
AYU is an internationally recognized quarterly journal dedicated to advancing research in Ayurveda. The journal covers a wide range of topics, including clinical and pharmacological research in Ayurveda's eight branches, herbal remedies, phytochemistry, and ethnomedicine.
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Sunil Kumar
Gajendra Singh
K. R. C. Reddy
AYU (Journal of Research in Ayurveda):
(An International Quarterly Journal of Research in Ayurveda)
Full text available for: Effect of Drakshavaleha in cyclophosphamide induced weight loss and reduction in crown-rump length in developing mice embryo
Year: 2013 | Doi: 10.4103/0974-8520.119686
Copyright (license): CC BY-NC-SA 4.0
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Summary of article contents:
Being an anti-mitotic and apoptosis inducing agent, Cyclophosphamide (CP) causes stunting in size and loss of body weight of the pups on intra-peritoneal injection (10 mg/kg) to pregnant mice on day 11 of gestation. Loss of body weight due to CP administration could be minimized by feeding Drakshavaleha (16 g/kg) orally to pregnant mice from day �0� to day �18� of their gestation. Recovery observed in terms of body weight of the pups was statistically significant (P < 0.001) in Drakshavaleha treated pups. Drakshavaleha also recovered the crown-rump length of the pups occurred due to CP administration. Growth retardation with decreased fetal weight was observed in all CP treated pups when compared with the controls. Keywords: Cyclophosphamide, Drakshavaleha, mice, Rasayana, vitamins, weight-loss
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Rasayana therapy, Kamala jaundice, Statistical Significance, Nutritional value, Teratogenic effect, Anti-oxidant Properties, Naimittika Rasayana, Ayurvedic Drug, Pandu (Anemia), Weight loss, Cyclophosphamide CP, Body weight loss, Crown-rump length, Anti-apoptotic properties, Micronutrient supplementation, Programmed cell death, Cyclophosphamide administration, Growth retardation, Multivitamin supplementation, Vitamin C supplementation, Ayurvedic concept of physiology, Intergroup comparison, Fetal malformation.