Significance of Preclinical study
Preclinical study refers to the research phase where the efficacy and safety of drugs or treatments are evaluated before they can be tested in humans. This stage often involves laboratory tests and the use of animal models, such as rats, to assess biological activity and safety. Preclinical studies are crucial for ensuring that promising drug leads, developed through combinatorial libraries, meet safety standards before moving on to clinical trials.
Synonyms: Preclinical research, Preclinical trial, Preliminary study, Experimental study, Preliminary research, Preclinical testing, Laboratory study, In vitro study, Animal study, Exploratory research
The below excerpts are indicatory and do represent direct quotations or translations. It is your responsibility to fact check each reference.
The concept of Preclinical study in scientific sources
The keyphrase "Preclinical study" relates to research conducted before clinical trials, emphasizing the evaluation of treatment effects and efficacy, such as with Tamra Bhasma, using animal models as a testing ground for safety and effectiveness.
From: World Journal of Pharmaceutical Research
(1) Research conducted prior to clinical trials, often using animal models to assess the efficacy of therapies.[1] (2) Research conducted before clinical trials that often involves laboratory tests and animal studies.[2] (3) Research stage in which promising drug leads developed through combinatorial libraries are evaluated.[3] (4) Research conducted to evaluate the effects of a treatment or substance before proceeding to human trials, often involving animal models.[4] (5) A type of research conducted on animal models to evaluate the efficacy and safety of a treatment before it is tested in humans.[5]
From: International Ayurvedic Medical Journal
(1) Research conducted prior to clinical trials, focusing on the effects and efficacy of treatments like Tamra Bhasma in animal models.[6]