Significance of Leukotoxin
Leukotoxin is a 114-kDa secreted heat-labile toxin produced by Aggregatibacter actinomycetemcomitans. This toxin is known for its ability to kill leukocytes and is recognized as a critical virulence factor in the development of periodontitis. Its role in the pathogenesis and progression of periodontal disease highlights its significance in oral health. Understanding the implications of leukotoxin is vital in studying and addressing periodontal disease effectively.
Synonyms: Biotoxin, Venom, Toxin
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The concept of Leukotoxin in scientific sources
Leukotoxin is a 114-kDa heat-labile toxin from Aggregatibacter actinomycetemcomitans that kills leukocytes, serving as a vital virulence factor in the pathogenesis and progression of periodontitis.
From: World Journal of Pharmaceutical Research
(1) A 114-kDa secreted heat-labile toxin produced by A. actinomycetemcomitans that can kill leukocytes and is considered a critical virulence factor in periodontitis.[1]
From: Journal of Indian Society of Periodontology
(1) A toxin produced by Aggregatibacter actinomycetemcomitans that plays a significant role in the pathogenesis and progression of periodontal disease.[2]