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Significance of ADMET profile

The ADMET profile refers to a set of pharmacokinetic parameters that include Absorption, Distribution, Metabolism, Excretion, and Toxicity. This profile helps evaluate how a drug behaves in the body and predicts its behavior in biological systems. Additionally, the ADMET profile serves as criteria for assessing the properties of various compounds, making it a crucial aspect in drug development and evaluation. Understanding the ADMET profile is important for determining the safety and effectiveness of pharmaceuticals.

Synonyms: Admet characteristics, Admet properties, Drug absorption, Distribution, Metabolism, Excretion, Toxicity profile

The below excerpts are indicatory and do represent direct quotations or translations. It is your responsibility to fact check each reference.

The concept of ADMET profile in scientific sources

Science Books

The ADMET profile encompasses pharmacokinetic parameters—Absorption, Distribution, Metabolism, Excretion, and Toxicity—essential for predicting a substance's behavior within biological systems and assessing drug efficacy and safety.

Significance in Scientific journals, articles, etc.:

From: World Journal of Pharmaceutical Research

(1) A set of criteria used to evaluate the Absorption, Distribution, Metabolism, Excretion, and Toxicity properties of compounds.[1] (2) A collection of pharmacokinetic parameters (Absorption, Distribution, Metabolism, Excretion, and Toxicity) that predict the behavior of the substances in biological systems.[2] (3) A set of pharmacokinetic parameters including Absorption, Distribution, Metabolism, Excretion, and Toxicity that indicate how a drug behaves in the body.[3]

From: Journal of Ayurveda and Integrative Medicine

(1) A characterization of compounds that includes their Absorption, Distribution, Metabolism, Excretion, and Toxicity profiles.[4]

This section includes scientific research in the field of healthcare, often involving traditional medicine systems such as Ayurveda, Unani, Siddha and Holistic health. It includes papers from scientific journals classified as either original, clinical or experimental research, review articles or case reports.