Herbal medicines Boswellia serrata and Nigella sativa fight bacteria.
Journal name: Journal of Indian Society of Periodontology
Original article title: Traditionally used herbal medicines with antibacterial effect on Aggegatibacter actinomycetemcomitans: Boswellia serrata and Nigella sativa
The Journal of Indian Society of Periodontology (JISP) publishes original scientific articles on periodontology (the study of supporting structures of teeth) and oral implantology. It is a bimonthly open-access journal with special issues for specific occasions.
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Original source:
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Bita Maraghehpour, Mina Khayamzadeh, Shamsoulmolouk Najafi, Mohammadjavad Kharazifard
Journal of Indian Society of Periodontology:
(A bimonthly open-access journal)
Full text available for: Traditionally used herbal medicines with antibacterial effect on Aggegatibacter actinomycetemcomitans: Boswellia serrata and Nigella sativa
Year: 2016 | Doi: 10.4103/jisp.jisp_12
Copyright (license): CC BY-NC-SA
Summary of article contents:
Introduction
The rising issue of antibiotic resistance has prompted the exploration of alternative treatments, particularly from ancient medicinal practices. Herbal medicine has gained renewed interest due to its potential antibacterial properties against various pathogens. In this study, the antibacterial effects of two traditionally used plants, Boswellia serrata (BS) and Nigella sativa (NS), were evaluated against Aggregatibacter actinomycetemcomitans (A.a), a key bacterium associated with aggressive periodontitis. The research highlights the significance of discovering effective antimicrobial agents in the face of growing bacterial resistance to standard antibiotic treatments.
Antibacterial Effects of Boswellia serrata and Nigella sativa
The study utilized a broth microdilution method to determine the minimum inhibitory concentration (MIC) of BS and NS against A.a. Results demonstrated that BS had an MIC of 512 μg/mL, while NS exhibited a much lower MIC of 128 μg/mL, indicating stronger antibacterial activity. The findings also revealed a significant difference in colony-forming units between the treated and control groups, confirming the efficacy of both plant extracts in inhibiting bacterial growth. This study contributes valuable evidence supporting the use of herbal remedies, particularly BS and NS, as potential ingredients in oral hygiene products aimed at combating periodontal pathogens.
Conclusion
This research underscores the promise of incorporating herbal medicines like Boswellia serrata and Nigella sativa into oral care strategies, particularly for patients suffering from aggressive forms of periodontitis. Their effective antibacterial properties against Aggregatibacter actinomycetemcomitans could offer a complementary or alternative approach to conventional antibiotic therapies. Nevertheless, the findings emphasize the need for further studies to explore the active components and their concentration variances from different geographical sources, to better understand their full potential and applications in oral health care.
FAQ section (important questions/answers):
What is the focus of the study involving Boswellia serrata and Nigella sativa?
The study evaluates the antibacterial effects of Boswellia serrata and Nigella sativa on the bacterium Aggregatibacter actinomycetemcomitans, which is known to be a significant pathogen in aggressive periodontitis.
How was the minimum inhibitory concentration (MIC) determined in the study?
The MIC for both Boswellia serrata and Nigella sativa was determined using the broth microdilution method, following Clinical and Laboratory Standards Institute guidelines to assess their effect on Aggregatibacter actinomycetemcomitans.
What were the results regarding the effectiveness of the herbal extracts?
The results showed that Boswellia serrata had an MIC of 512 μg/mL, while Nigella sativa had an MIC of 128 μg/mL, indicating that both extracts exert antibacterial effects against Aggregatibacter actinomycetemcomitans.
What implications do the findings have for oral hygiene products?
The findings suggest that both Boswellia serrata and Nigella sativa could be beneficial ingredients in oral hygiene products, particularly for managing issues related to aggressive periodontitis due to their antibacterial properties.
What are the limitations mentioned in the study?
The study acknowledges limitations such as the variations in active components of herbs from different regions and the use of crude extracts, which may impact the comparability of MIC results with other studies.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “Herbal medicines Boswellia serrata and Nigella sativa fight bacteria.�. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Table:
Table refers to a structured arrangement of data in rows and columns, which is essential in presenting experimental results in a clear and concise manner. In scientific studies, tables are used to summarize key data such as minimum inhibitory concentrations, comparisons between treatment groups, or other quantitative findings to facilitate data interpretation.
2) Study (Studying):
Study refers to the systematic investigation of a specific topic or phenomenon, often involving the hypothesis, methodology, analysis, and conclusions drawn from the research. In the context of this document, it implies a detailed examination of the antibacterial effects of Boswellia serrata and Nigella sativa on Aggregatibacter actinomycetemcomitans.
3) Antibiotic (Antibacterial):
Anti-bacterial refers to the capacity to combat or eliminate bacteria. This term underscores the main focus of the study, aiming to evaluate the effectiveness of certain herbal extracts against harmful bacterial strains, particularly those linked to serious dental diseases.
4) Medicine:
Medicine signifies the science and practice of diagnosing, treating, and preventing diseases. It underscores the importance of integrating traditional knowledge of medicinal plants with modern scientific inquiry, as noted in the study, which investigates herbal alternatives in light of rising antibiotic resistance.
5) Disease:
Disease refers to a pathological condition of a bodily part, often characterized by specific signs and symptoms. The relevance in this study focuses on aggressive periodontitis, a condition linked to the pathogenicity of Aggregatibacter actinomycetemcomitans, which the herbs aim to combat.
6) Aureus:
Aureus typically refers to Staphylococcus aureus, a common bacteria known for causing infections. Although not the primary focus of this study, the mention of various bacteria, including aureus, indicates the broader context of antibacterial research across multiple bacterial species, including ideal targets in traditional medicine.
7) Post:
Post generally refers to the period or condition following a specific event or process. In this context, it indicates findings or effects observed after treatment with herbal extracts. It underscores the significance of evaluating both immediate and long-term impacts of treatments in research contexts.
8) Activity:
Activity refers to the level of action or effectiveness exhibited by a substance or organism. Here, it pertains to the antibacterial activity of Boswellia serrata and Nigella sativa, which is critical for gauging their potential therapeutic applications against specific pathogenic bacteria.
9) Species:
Species denotes a group of organisms sharing common characteristics and capable of interbreeding. In this document, it relates to the specific bacterial strains, like Aggregatibacter actinomycetemcomitans and other studied organisms, indicating the focus on defining targeted interventions against these pathogens.
10) Powder:
Powder refers to a fine, dry substance composed of finely divided particles, often used in the preparation of medicinal extracts. The relevance of this term highlights the methodology aspect of the study where herbal materials were processed into powder form for extraction and analysis.
11) Tulsi:
Tulsi, also known as Ocimum sanctum, is a revered herb in traditional medicine, noted for its numerous health benefits. Its mention in the document signifies the exploration of various herbal treatments and their antibacterial properties that may serve as adjuncts for dental health.
12) Account:
Account signifies a record or explanation of something. In this context, it emphasizes the necessity to consider and document the effects of herbal treatments thoroughly, assessing how they might serve roles in strategies for oral hygiene, especially against specific bacteria known to contribute to diseases.
13) Hygiene (Hygienic):
Hygiene refers to practices that promote health and prevent disease, especially through cleanliness. The study implies that incorporating herbal extracts into hygiene products could offer additional antibacterial protection, thereby enhancing oral health, particularly for individuals at risk of periodontal diseases.
14) Water:
Water plays a crucial role in various biological and chemical processes. While its direct relevance may not be expounded in the text, it generally pertains to the solvent used for extracting active components from herbal materials, emphasizing its importance in the preparation of herbal extracts.
15) Musa paradisiaca:
Musa paradisiaca, commonly known as banana, is mentioned concerning its antimicrobial properties as observed in other studies. This reference adds to a broader understanding of the potential for various plant species as effective agents against specific bacterial infections, including those studied in this work.
16) Cuminum cyminum:
Cuminum cyminum, or cumin, is a spice known for its culinary and medicinal properties. Its mention in the research context expands on the theme of exploring various plant-derived compounds with antibacterial potential, challenging preconceived notions of the exclusive therapeutic value of specific herbs.
17) Ocimum sanctum:
Ocimum sanctum, or sacred basil (Tulsi), has been used traditionally for its potential health benefits. Mentioning this herb exemplifies the study's emphasis on utilizing established herbal medicines known for their antimicrobial effectiveness, contributing to the ongoing exploration of alternative treatments.
18) Discussion:
Discussion pertains to the section of the study where results are interpreted, implications are considered, and future directions are suggested. It facilitates a deeper understanding of the findings and allows for the integration of new knowledge into existing frameworks concerning antimicrobial treatments.
19) Substance:
Substance refers to a material with distinct properties; in this context, it highlights various extracts or compounds under examination for their antibacterial properties. This word encapsulates the essence of the study, focusing on herbal compositions as potential treatment options.
20) Science (Scientific):
Science refers to the systematic study of the structure and behavior of the physical and natural world through observation and experimentation. It serves as the foundation for the study's methodology, emphasizing evidence-based approaches to investigate the antibacterial effects of traditional herbs.
21) Family:
Family in a biological context refers to a group of related organisms. This relevance highlights the classification of various plants explored in the study, which belong to particular families known for their medicinal properties, providing insights into potential biological similarities and therapeutic applications.
22) Fever:
Fever denotes a heightened body temperature often indicating infection. While not the focus of the study, its mention underscores the historical context of herbal medicine in treating fever and its role as a symptom of infections caused by pathogens being studied.
23) Blood:
Blood represents a vital fluid transporting nutrients and oxygen through the body. Mentioning blood can indicate broader physiological responses related to infections and the importance of addressing pathogenic bacteria within the context of systemic health and local disease management.
24) Raja:
Raja likely refers to an author or contributor of a cited work mentioned in the discussion. This inclusion illustrates the interconnectedness of scientific research, where studies build upon or reference previous investigations to provide a comprehensive understanding of the topic at hand.
25) Musha (Musa, Musá):
Musa generally refers to the genus of banana plants, which includes species known for their nutritional and medicinal benefits. Its relevance relates to the exploration of various herbal treatments reflecting the diversity of plant sources that are being investigated for their antibacterial properties.
26) Food:
Food denotes substances consumed for nutritional support. In a broader sense, its mention reflects the interconnectedness of diet and health, highlighting how various herbs and plants traditionally used as food sources may also provide therapeutic benefits, aligning with the study’s focus on herbal medicine.
Other Science Concepts:
Discover the significance of concepts within the article: �Herbal medicines Boswellia serrata and Nigella sativa fight bacteria.�. Further sources in the context of Science might help you critically compare this page with similair documents:
Boswellia serrata, Nigella sativa, Herbal medicine, Statistical analysis, Control group, Anti-inflammatory properties, Antimicrobial properties, Minimum inhibitory concentration, Synergistic effect, Aggregatibacter actinomycetemcomitans, Active metabolite, Polymicrobial infection, Broth microdilution method, Aggressive periodontitis, Oral hygiene product, Tukey's honest significant difference.