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Brahmi Vati for Generalized Anxiety Disorder: A Clinical Trial

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Journal name: Journal of Ayurveda and Integrative Medicine
Original article title: Efficacy of Brahmi vati in generalised anxiety disorder � Randomized double blind comparative clinical trial
The Journal of Ayurveda and Integrative Medicine (JAIM) is an open-access publication promoting collaboration between Ayurveda, traditional medicine, and biomedicine, publishing research on integrative health sciences
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Original source:

This page only sums up technical details and meta-data hence you should visit the source to read the original article which includes the author, publication date, notes and references.

Author:

Siddhi G. Khot, Basavaraj R. Tubaki, Varsha B. Gonugade


Journal of Ayurveda and Integrative Medicine:

(A monthly peer-reviewed publication)

Full text available for: Efficacy of Brahmi vati in generalised anxiety disorder � Randomized double blind comparative clinical trial

Year: 2022 | Doi: 10.1016/j.jaim.2022.100552

Copyright (license): CC BY-NC-ND 4.0


Download the PDF file of the original publication


Glossary definitions and references:

Scientific and Ayurvedic Glossary list for “Brahmi Vati for Generalized Anxiety Disorder: A Clinical Trial�. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.

1) Anxiety:
Anxiety is a prevalent mental health condition characterized by excessive worry and fear. It significantly impacts individuals' social and professional lives. Understanding anxiety is crucial in developing effective treatments, especially in subjective experiences like generalized anxiety disorder (GAD), as explored in studies involving Ayurvedic medications.

2) Brahmi:
Brahmi, scientifically known as Bacopa monnieri, is a vital herb in Ayurveda praised for its cognitive-enhancing properties. It is believed to improve memory, reduce anxiety, and promote mental clarity. Ayurvedic practitioners utilize Brahmi in various formulations, making it integral for studies focused on anxiety management.

3) Study (Studying):
A study indicates a systematic investigation aiming to validate hypotheses or explore health treatments. Research evaluates the effectiveness and safety of interventions, providing reliable information for clinical practice. The significance lies in revealing how traditional medicine like Ayurveda can address contemporary issues such as anxiety disorders.

4) Table:
Tables in research documents succinctly present data, comparisons, and results. They offer an organized way to interpret complex information such as patient demographics, treatment outcomes, or statistical analyses. The clarity of tables helps readers quickly grasp findings, making them essential for scientific communication in studies.

5) Vati:
Vati refers to a type of Ayurvedic formulation typically presented in pill or tablet form. This dosage form is convenient for administration, allowing precise dosage. Vati forms are often utilized in various treatments to manage conditions, aligning with the principles derived from ancient Ayurvedic texts.

6) Ayurveda (Ayus-veda):
Ayurveda is an ancient Indian system of medicine emphasizing holistic health and wellness. It integrates the concepts of balance among body, mind, and spirit. In contemporary research, Ayurveda's methodologies are explored for treating various ailments, particularly mental health disorders, showcasing its relevance in modern medicine.

7) Vataka:
Vataka is a term in Ayurveda that generally refers to therapeutic formulations, specifically those in tablet or pill form. These preparations are crafted to achieve specific health benefits, often rooted in Ayurvedic traditions. Their formulations may blend multiple herbs to enhance efficacy against various disorders.

8) Drug:
In medicine, a drug is a substance utilized for diagnosis, treatment, or prevention of diseases. In the context of mental health, understanding pharmacological treatments, including Ayurvedic formulations, broadens the scope of managing conditions like anxiety. Research studies assess their efficacy and safety profiles.

9) Blood:
Blood tests play a crucial role in medical evaluations, providing insights into various health conditions. They help assess systemic health before and after treatments, especially in clinical trials for anxiety disorders, allowing identification of potential underlying health issues affected by medications.

10) Quality:
Quality, in health contexts, refers to the standard of care and outcomes achieved. Evaluating the quality of life in patients with anxiety disorders is vital, as it reflects the overall effectiveness of treatments. Quality indices help assess the emotional and physical well-being of individuals.

11) Life:
Life quality encompasses the overall well-being of individuals, including physical, mental, and social aspects. Research examining interventions for anxiety focuses on improving life quality through symptom management, ensuring that therapeutic approaches not only alleviate symptoms but also enhance overall life satisfaction.

12) Depression:
Depression commonly coexists with anxiety disorders, complicating clinical presentations and treatment strategies. Understanding the interplay between anxiety and depression is crucial for developing holistic treatment interventions in Ayurveda, as both mental health conditions significantly impact patients' quality of life and well-being.

13) Activity:
Activity in medical studies refers to the physiological and psychological responses to treatments or interventions. Monitoring activity levels helps assess improvements in physical and mental health during treatment. This includes evaluating changes in anxiety symptoms, sleep patterns, and overall life engagement post-treatment.

14) India:
India's rich tradition of Ayurveda provides a holistic approach to health, deeply integrating natural remedies for various ailments. Understanding its historical significance enables contemporary research to explore its benefits for mental disorders like anxiety, fostering integration of traditional methods into modern therapeutic practices.

15) Disease:
Diseases encompass a range of health conditions that disrupt normal bodily functions. Understanding the pathology of mental health diseases, specifically anxiety disorders, informs effective treatment strategies. Research plays a vital role in identifying diseases' causes, prevalence, and potential remedies through both pharmaceutical and herbal approaches.

16) Mental disorder:
Mental disorders are conditions that affect mood, thinking, and behavior, including anxiety and depression. Studying these disorders using Ayurvedic principles offers insights into alternative treatments, emphasizing holistic wellness and the mind-body connection. The growing recognition of mental disorders necessitates comprehensive intervention strategies.

17) Medicine:
Medicine refers to the science of diagnosing, treating, and preventing diseases and injuries. It encompasses various fields, including traditional practices like Ayurveda, which offers unique insights into holistic health management. Exploring Ayurvedic medicine enhances understanding and treatment approaches for mental health conditions.

18) Sharman (Sarma, Sharma, Sarman):
Sharma is a common surname in India, often associated with practitioners and researchers in various fields, including medicine. In the context of Ayurveda, individuals named Sharma may contribute significantly to understanding traditional practices, focusing on mental health management and enhancing therapeutic effectiveness through research.

19) Indian:
Indian traditions, including Ayurveda, offer a vast repertoire of medical practices, emphasizing holistic care. The country's rich cultural heritage plays a pivotal role in mental health strategies, especially regarding anxiety and depression management, integrating ancient wisdom and contemporary medical practices.

20) Ghana:
In Ayurvedic contexts, Ghana refers to a concentrated form of an herbal preparation, typically resulting in a powder or paste. This preparation method enhances bioavailability and effectiveness of the medicine. Understanding this term is crucial for evaluating the efficacy of Ayurvedic treatments in clinical studies.

21) Vaca:
Vacha, or Acorus calamus, is an important Ayurvedic herb noted for its cognitive-enhancing and anxiolytic properties. It is used in formulations targeting mental clarity and health. Understanding Vacha's properties enriches the exploration of Ayurveda in treating anxiety disorders and improving mental wellness.

22) Nardostachys jatamansi (Nardostachys jatamamsi):
Nardostachys jatamansi, known as Jatamansi, is a significant herb in Ayurveda recognized for its neuroprotective and calming properties. It is frequently employed in treating anxiety and promoting sleep, making it relevant in studies focused on improving mental health through herbal interventions.

23) Mental health:
Mental health encompasses emotional, psychological, and social well-being. It influences how we think, feel, and act, and determines how we handle stress, relate to others, and make choices. Exploring mental health through Ayurveda offers alternative methods to promote overall wellness.

24) Education:
Education in the context of mental health includes understanding various treatment modalities, including traditional and modern practices. Educating patients and practitioners about anxiety disorders enhances awareness, facilitates better management strategies, and fosters an integrated approach toward mental health care.

25) Varanasi (Varanashi):
Varanasi, a historical city in India, is renowned for its cultural and educational significance. It serves as a vital hub for Ayurvedic medicine and research, attracting scholars and practitioners focusing on holistic health methodologies, which directly impacts the understanding of mental health treatments.

26) Writing:
Writing in medical journals and studies is crucial for disseminating research findings. It facilitates knowledge-sharing and contributes to the academic discourse surrounding mental health treatments, enhancing the understanding of various methodologies, including traditional approaches like Ayurveda for anxiety management.

27) Worry (Worried, Worrying):
Worry is a common symptom of anxiety disorders, characterized by persistent and excessive concerns about various aspects of life. Understanding worry's impact is essential for evaluating treatments in clinical studies, especially those focusing on holistic approaches to managing anxiety through Ayurveda.

28) Line:
Line in research studies often refers to a methodological framework or theoretical approach that guides the exploration and evaluation of health interventions. Defining the line of inquiry is essential in establishing the significance and relevance of findings related to mental health treatments.

29) Post:
In research contexts, a post often refers to the time after an intervention or treatment duration. Analyzing post-treatment outcomes is critical to determine the effectiveness of therapies, especially in studies assessing the impact of Ayurvedic medicines on anxiety disorders.

30) Withania somnifera:
Withania somnifera, commonly known as Ashwagandha, is an adaptogenic herb recognized for its ability to reduce stress and anxiety. It holds a prominent position in Ayurvedic medicine, addressing mental health issues and enhancing overall wellness, making it integral to studies targeting anxiety.

31) Karnataka:
Karnataka is a significant state in India where traditional practices of Ayurveda are widely studied and practiced. It is a leading center for Ayurvedic education and research, contributing substantially to advancing knowledge about herbal treatments for mental health challenges like anxiety.

32) Prakarana:
Prakarana refers to chapters or sections in Ayurvedic texts detailing the preparation and application of medicinal formulations. Understanding Prakarana is essential for practitioners and researchers in the context of studying the efficacy and guidelines for specific treatments in mental health.

33) Rasayana (Rasa-ayana):
Rasayana is a branch of Ayurveda focused on rejuvenation and longevity. It emphasizes herbal remedies and lifestyle changes to enhance mental and physical well-being. Rasayana therapies are particularly relevant for treating chronic conditions like anxiety, enhancing cognitive functions, and quality of life.

34) Water:
Water plays a crucial role in Ayurvedic treatments, often used for diluting herbal preparations or as a vehicle for administering medications. It is essential for hydration and is seen as a component of holistic health, supporting overall bodily functions during treatment interventions.

35) Rules:
Rules regarding ethical standards and methodologies in research ensure valid and reliable results. Following established rules is vital for conducting research in healthcare, including exploring Ayurvedic treatments, enhancing credibility and reproducibility of findings associated with mental health interventions.

36) Shri (Sri, Sr):
Shri is a respectful honorific commonly used in India, particularly in the context of addressing individuals in a culturally appropriate manner. In Ayurvedic literature, it is often prefixed to names, denoting respect and tradition, emphasizing the cultural roots of healing practices.

37) Vata:
Vata, one of the three doshas in Ayurvedic medicine, represents the air and space elements. It is crucial for regulating bodily functions and maintaining balance. Understanding Vata's characteristics aids in diagnosing and treating conditions that manifest due to its imbalance, such as anxiety.

38) Pur:
Poor mental health status, characterized by symptoms like anxiety and depression, significantly impairs quality of life. Evaluating and addressing poor mental health outcomes is essential for developing effective treatments that enhance overall well-being, particularly in the context of traditional medicine like Ayurveda.

39) Tirunavukkaracu (Tiru-navukkaracu, Thirunavukkarasu):
Thirunavukkarasu is often associated with Ayurvedic practitioners or researchers involved in significant contributions related to traditional medicine. Notable individuals with this name may be pivotal in advancing knowledge and understanding of practices that integrate Ayurveda with modern therapeutic approaches.

40) Acorus calamus:
Acorus calamus, commonly known as Vacha, is recognized in Ayurveda for its cognitive-enhancing and anxiolytic properties. It is frequently included in formulations addressing mental clarity and anxiety, underscoring its relevance in contemporary research for treating anxiety disorders.

41) Shankhapushpi (Sankhapuspi, Samkhapuspi):
Shankhapushpi is an Ayurvedic herb valued for its neuroprotective and cognitive-enhancing effects. Used in formulations aimed at managing stress and improving mental health, its role in reducing anxiety symptoms highlights its relevance in studies focusing on alternative treatments for mental disorders.

42) Venkataraman:
Venkataraman is typically a surname of Indian origin, often linked to practitioners or researchers in various fields, including medicine. Individuals with this surname may contribute to significant research in Ayurvedic practices and the development of treatment strategies for mental health issues.

43) Pharmacology:
Pharmacology is the branch of medicine that studies the effects of drugs on biological systems. Understanding pharmacological principles is essential for evaluating the efficacy and safety of Ayurvedic formulations aimed at treating anxiety and depression, integrating traditional knowledge with scientific inquiry.

44) Ashvagandha (Asvagandha, Ashwagandha, Ashvagamdha, Ashva-gandha):
Ashwagandha, or Withania somnifera, is a renowned adaptogenic herb used widely in Ayurveda to alleviate stress and anxiety. Its efficacy in enhancing mental health outcomes situates it as a crucial element of research targeting comprehensive approaches to managing anxiety disorders.

45) Kandikattu:
Kandikattu refers to a locality or practitioner relevant within Ayurvedic traditions. Understanding regional context enriches the exploration of traditional therapies and can influence local practices in treating anxiety disorders, highlighting the diversity of Ayurvedic medicine.

46) Shrinivasa (Shri-nivasa, Srinivasa):
Srinivasa is a common Indian name often associated with notable scholars, practitioners, or researchers in Ayurveda. The contributions of individuals with this name to Ayurvedic studies aid in the understanding of treatments for mental health, particularly anxiety and stress management.

47) Substance:
Substance typically refers to any specific drug or material used in treatment. In the context of mental health, understanding the role of various substances, including herbal formulations, is critical for developing effective therapies for conditions such as anxiety and depression.

48) Samgraha (Sangraha):
Sangraha refers to compilations or collections, especially in the context of Ayurvedic texts. Comprehensive understanding of Sangraha aids practitioners in accessing knowledge regarding treatment formulations, posology, and therapeutic practices, ultimately supporting enhanced patient care in mental health contexts.

49) Sanskrit:
Sanskrit is the classical language of India, integral to the transmission of Ayurvedic knowledge through ancient texts. Proficiency in Sanskrit allows practitioners and researchers to interpret foundational texts accurately, ensuring the integrity of Ayurvedic treatments for mental disorders like anxiety.

50) Samhita:
Samhita denotes collections of verses or aphorisms, particularly in Ayurveda. They serve as foundational texts for the practice, detailing medicinal ingredients and methodologies. Understanding Samhita is vital for practitioners in applying Ayurvedic principles effectively to treat conditions like anxiety.

51) Amalaki:
Amalaki, or Emblica officinalis, is a revered herb in Ayurveda known for its antioxidant and health-promoting properties. It plays a significant role in balancing doshas and enhancing overall health, making it a valuable component in formulations aimed at stress and anxiety management.

52) Channel:
Channel in pharmacology often refers to pathways that allow substances to affect body functions. Understanding drug channels enhances the appreciation of how Ayurvedic formulations interact at physiological levels to influence mental health, particularly in treating anxiety disorders.

53) Filling (Filled):
Filling refers to the process of encapsulating herbal powders into tablets or capsules in Ayurveda. This method ensures precise dosage, making formulations user-friendly and effective for mental health treatments, enhancing adherence to prescribed regimens.

54) Science (Scientific):
Science in the context of Ayurveda refers to the systematic study of health and medicine, emphasizing evidence-based practices. Integrating scientific exploration with traditional Ayurvedic methods enhances understanding of treatment efficacy for mental health conditions, fostering advancements in holistic healthcare.

55) Tagara:
Tagara, or Valeriana wallichii, is an Ayurvedic herb known for its sedative and calming effects. It is used to manage sleep and anxiety disorders, highlighting the importance of plant-based treatments within Ayurveda for enhancing mental health and well-being.

56) Prabha:
Prabha is a name often linked to Ayurvedic practitioners or researchers contributing to the field's advancements. The work of individuals named Prabha may focus on the integration and application of traditional knowledge, especially related to mental health treatments.

57) Mishra (Misra):
Mishra is a common surname in India, often associated with practitioners or researchers in medicine. Individuals with this name may contribute to Ayurvedic studies, promoting a deeper understanding of how traditional remedies can be effective in alleviating anxiety and related disorders.

58) Sthana:
Sthana refers to anatomical or physiological locations. Understanding Sthana is essential in Ayurveda for accurately diagnosing conditions and applying treatments, especially in mental health contexts, where precise knowledge can dictate effective intervention strategies.

59) Vimana:
Vimana refers to chapters in Ayurvedic texts that deal with specialized topics or medicinal practices. Mastery of Vimana content is essential for practitioners to successfully navigate treatment methodologies, particularly those addressing mental health challenges such as anxiety disorders.

60) Anidra:
Anidra, or insomnia, is a condition referenced in Ayurvedic texts, often relating to anxiety disorders. Understanding its implications and treatments within Ayurveda can lead to better management strategies for individuals struggling with sleep-related issues linked to anxiety.

61) Medium:
Medium, in therapeutic contexts, often refers to the method or content format through which treatments are delivered. In Ayurveda, identifying an appropriate medium for herbal formulations can significantly influence efficacy, particularly concerning mental health interventions.

62) Pitta:
Pitta is one of the three doshas in Ayurveda, representing fire and water elements. Understanding Pitta's characteristics helps in diagnosing and managing anxiety-related disorders, allowing for personalized treatment plans that restore balance to the individual’s constitution.

63) Kapha:
Kapha is one of the three doshas in Ayurveda, associated with earth and water elements. Recognizing Kapha imbalances is essential for developing appropriate interventions for anxiety treatments, demonstrating Ayurveda's holistic approach in addressing mental health conditions.

64) Chang:
Chang is a surname commonly found among individuals engaged in various professional fields, including research. In studies relating to Ayurveda and mental health, contributors with the surname Chang might help advance understanding through scientific methodologies and interdisciplinary collaborations.

65) Kuca:
Kuca refers to a locality or practitioner often associated with the Ayurvedic tradition. Recognizing regional practices and contributions enhances understanding of localized therapeutic approaches, particularly how they can influence treatments for mental health issues.

66) Sara (Shara):
Sara in Ayurveda refers to essence or core principles regarding treatment modalities. Understanding the concept of Sara is fundamental for practitioners in effectively applying Ayurvedic principles to improve mental health outcomes, ensuring a deep comprehension of patient needs.

67) Food:
Food plays a significant role in Ayurveda, emphasizing diet’s impact on health and wellness. Understanding dietary recommendations helps inform comprehensive treatment plans for managing mental health issues, particularly anxiety, illustrating the confluence between nutrition and psychological well-being.

68) Diet:
Diet in Ayurveda comprises specific food habits believed to influence health conditions, including mental well-being. Tailored dietary practices enhance treatment efficacy for anxiety and other disorders, reflecting Ayurveda’s holistic framework integrating physical health with mental health management.

69) Emblica officinalis:
Emblica officinalis, known as Amalaki, is a potent herb in Ayurveda known for its rejuvenating properties and benefits to mental health. Its antioxidant properties contribute to stress reduction, making it an essential component for formulating treatments targeting anxiety and overall well-being.

70) Valeriana wallichii:
Valeriana wallichii, known as Tagara, is prominent in Ayurveda for its sedative properties. Its application in managing sleep disturbances and anxiety illustrates the relevance of herbal therapies in addressing mental health challenges and enhancing quality of life for affected individuals.

71) Peer review:
Peer review is a critical process in scholarly publishing, ensuring that research is evaluated by experts before publication. It enhances the credibility and validity of studies investigating Ayurvedic practices, ensuring that findings related to mental health treatments meet rigorous scientific standards.

72) Pharmacotherapy:
Pharmacotherapy refers to the treatment of diseases with medications. Integrating pharmacotherapy with Ayurvedic approaches illustrates the potential for a comprehensive treatment strategy to manage mental health disorders, particularly anxiety, promoting the blending of traditional and modern medical practices.

73) Pharmacological:
Pharmacological studies explore how drugs affect physiological processes. Understanding pharmacological actions of Ayurvedic medications enhances insights into their therapeutic mechanisms, particularly concerning substances used for treating anxiety and related mental health challenges.

74) Vimanasthana (Vimana-sthana):
Vimana-sthana refers to specific sections in Ayurvedic texts dedicated to advanced therapeutic methods. Knowledge of Vimana-sthana content is essential for practitioners seeking to apply in-depth Ayurvedic practices and explore their relevance in treating conditions like anxiety and promoting mental health.

75) Padmakesara (Padma-kesara, Padmakeshara, Padma-keshara):
Padmakeshara is a term potentially linked to Ayurvedic formulations involving specific herbs. Studying ingredients like Padmakeshara can broaden understanding of Ayurvedic strategies for treating anxiety and enhancing overall mental well-being, showcasing the uniqueness of traditional medicinal practices.

[Note: The above list is limited to 75. Total glossary definitions available: 117]

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Discover the significance of concepts within the article: �Brahmi Vati for Generalized Anxiety Disorder: A Clinical Trial�. Further sources in the context of Science might help you critically compare this page with similair documents:

Informed consent, Statistical analysis, Generalized Anxiety Disorder, Erythrocyte sedimentation rate, Hamilton Anxiety Rating Scale, Serum Creatinine, Institutional ethics committee, Pittsburgh Sleep Quality Index, Sample size calculation, Liver function test, WHO quality of life BREF, Brahmi vati, Epworth sleepiness scale, Clinical laboratory, Adverse event, Randomized double blind controlled trial, GAD 7 Scale.

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