A Clinical Study on Efficacy of Ajeya Ghrita in Dushivisha Janya Lakshana
Journal name: Ayushdhara
Original article title: A Clinical Study on Efficacy of Ajeya Ghrita in Dushivisha Janya Lakshana
AYUSHDHARA is an international peer-reviewed journal. It focuses on research in Ayurveda, Yoga, Unani, Siddha, Homeopathy, Allopathy, and Pharmaceutical Sciences.
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Garima
MD Scholar, Dept. of Agad tantra evum Vidhivaidhyaka, Uttarakhand Ayurved University, Harrawala, Dehradun, Uttarakhand, India.
Tiwari R.C
Professor and HOD, Dept. of Agad tantra evum Vidhivaidhyaka, Uttarakhand Ayurved University, Harrawala, Dehradun, Uttarakhand, India.
Chandra Mahesh
Assistant Professor, Department of Rasa sastra, Uttarakhand Ayurved University, Harrawala, Dehradun, Uttarakhand, India.
Ayushdhara:
(A peer-reviewed, bi-monthly open-access journal)
Full text available for: A Clinical Study on Efficacy of Ajeya Ghrita in Dushivisha Janya Lakshana
Year: 2021 | Doi: 10.47070/ayushdhara.v8i3.748
Copyright (license): CC BY-NC-SA 4.0
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Summary of article contents:
Introduction
Cumulative toxicity, referred to in Ayurveda as Dushivisha, poses a significant health risk in modern life due to environmental pollutants, consumption of processed foods, and lifestyle choices. Various substances, including fast food, alcohol, tobacco, and pesticides contribute to this condition, leading to an array of health challenges by aggravating the body's doshas and disrupting its dhatus (tissues). Recognizing the detrimental effects of these toxins, Acharya Sushruta advocated for Ajeya Ghrita as an effective remedy for managing Dushivisha-related diseases. This study focuses on evaluating the efficacy of Ajeya Ghrita against the symptoms arising from Dushivisha in a cohort of affected individuals.
Efficacy of Ajeya Ghrita
Ajeya Ghrita, as mentioned in the traditional texts, exhibits properties that aid in alleviating symptoms associated with Dushivisha. The preparation, recognized for its antioxidant capabilities, was administered to 30 patients divided into two groups, each receiving either Ajeya Ghrita or a standard drug (Murchitgo-ghrita) for a duration of 30 days. The study highlighted that patients treated with Ajeya Ghrita experienced notable improvements in symptoms such as indigestion (Avipaka), skin allergies (Kotha), and weakness (Daurbalya). Statistical analyses revealed significant results, particularly in reducing the severity of indigestion and skin allergic reactions, showcasing the potential of Ajeya Ghrita in supporting detoxification processes and restoring balance in the body.
Comparison with Standard Treatment
While both Ajeya Ghrita and Murchitgo-ghrita demonstrated effects on symptom alleviation, the study found Ajeya Ghrita significantly more effective in treating symptoms of indigestion and skin conditions compared to the standard drug. In laboratory tests, patients receiving Ajeya Ghrita also showed improvements in biochemical markers, such as hemoglobin levels and total leucocyte count, indicating an enhancement in their overall health status. In contrast, the standard group exhibited comparably lesser improvement. This comparative analysis underscores the effectiveness of Ajeya Ghrita as a valuable therapeutic option for manifestations of Dushivisha, while also validating classic Ayurvedic approaches to modern health challenges.
Conclusion
The findings of this clinical study affirm the traditional claims surrounding Ajeya Ghrita, asserting its efficacy in treating Dushivisha-related symptoms such as premature aging, skincal conditions, fever, and weakness. Patients demonstrated significant improvements in various subjective and objective parameters after the intervention. Moreover, the study supports the continued use of Ayurvedic formulations in contemporary medical practice, particularly in addressing the complex issues caused by modern dietary and environmental factors. Overall, Ajeya Ghrita is positioned as a promising remedy for cumulative toxicity and related health conditions, encouraging further research and exploration in Ayurvedic medicine.
FAQ section (important questions/answers):
What is the focus of the clinical study conducted?
The clinical study focuses on the efficacy of Ajeya Ghrita in treating Dushivisha Janya Lakshana, which are symptoms arising from cumulative toxicity, primarily due to pesticide exposure and other environmental toxins.
What were the main findings regarding Ajeya Ghrita's effectiveness?
Ajeya Ghrita showed significant improvement in symptoms like indigestion, skin allergies, and weakness. The results indicated that 6.67% of patients achieved complete remission, with notable reductions in symptom severity compared to the control group.
How was the study conducted and what were the criteria?
The study involved 30 patients aged 18-60 with symptoms of Dushivisha. Patients were divided into two groups, one receiving Ajeya Ghrita and the other Murchit Ghrita, with evaluations based on specific symptoms and laboratory tests before and after treatment.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “A Clinical Study on Efficacy of Ajeya Ghrita in Dushivisha Janya Lakshana�. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Hair:
Ajeya Ghrita showed significant improvement in symptoms like hair loss and greying of hair. It prevents these issues due to its properties in treating Dushivisha Janya Lakshana.
2) Ghrita (Ghrta):
It is a form of medicated ghee, used in Ayurvedic treatments. Ajeya Ghrita is specifically effective in managing symptoms caused by cumulative poison (Dushivisha).
3) Food:
Modern food habits involving processed, fast, and junk food contribute to Dushivisha (cumulative toxicity), which the study addresses by analyzing the efficacy of Ajeya Ghrita.
4) Dushivisha (Dusivisa):
A specific type of cumulative poison. The study investigates Ajeya Ghrita's efficacy in managing symptoms resulting from Dushi-visha.
5) Fever:
One of the symptoms related to Dushivisha Janya Lakshana which Ajeya Ghrita has been found to alleviate.
6) Drug:
Ajeya Ghrita was the drug studied in the trial to evaluate its effectiveness against symptoms of Dushivisha Janya Lakshana.
7) Pesticide:
Main modern source of cumulative poison contributing to Dushivisha, affecting food and causing health issues.
8) Vomiting:
Referred to as Chardi in the study, recurrent vomiting over a year was considered a symptom of Dushivisha Janya Lakshana targeted by Ajeya Ghrita.
9) Kotha:
Skin allergies termed as Kotha are recurring symptoms of Dushivisha Janya Lakshana, shown to be treatable by Ajeya Ghrita.
10) Irritation:
Symptoms like eye irritation are considered under Dushivisha Janya Lakshana, which Ajeya Ghrita aims to alleviate.
11) Daurbalya:
Referred to as weakness, Daurbalya is a symptom of Dushivisha Janya Lakshana. Ajeya Ghrita has shown significant improvement in alleviating this symptom.
12) Avipaka:
Indigestion, also known as Avipaka, is a recurring symptom in Dushivisha Janya Lakshana which Ajeya Ghrita aims to treat effectively.
13) Disease:
The trial treats diseases resulting from Dushivisha, a cumulative poison, using Ajeya Ghrita to manage various symptoms.
14) Kandughna (Kandu-ghna):
Indicating anti-pruritic properties, several ingredients in Ajeya Ghrita have Kandughna properties, which aid in treating skin allergies.
15) Vishaghna (Visaghna, Visha-ghna):
It refers to anti-toxin properties. Ajeya Ghrita contains multiple ingredients with Vishaghna properties to combat symptoms caused by toxins.
16) Lakshana (Laksana):
Symptoms or signs of a condition. The study evaluates the efficacy of Ajeya Ghrita in addressing Dushivisha Janya Lakshana or symptoms.
17) Thirst:
Excessive thirst, termed Trishna, is a symptom of Dushivisha Janya Lakshana targeted in the study using Ajeya Ghrita.
18) Guna:
Qualities or properties of substances in Ayurveda. Ajeya Ghrita's effectiveness is due to its various Guna such as Laghu, Tikshna, and Snigdha.
19) Toxicity:
Refers to the harmful effects of substances. The study focuses on treating symptoms resulting from pesticide toxicity using Ajeya Ghrita.
20) Trishna (Trsna):
Increased thirst due to Dushivisha, targeted and relieved through the administration of Ajeya Ghrita.
21) Allergy:
[see source text or glossary: Allergy]
22) Chardi:
Vomiting, a recurring symptom analyzed in the study of Ajeya Ghrita's efficacy against Dushivisha Janya Lakshana.
23) Kapha:
One of the three Doshas in Ayurveda, often involved in the pathogenesis of Dushivisha. Ajeya Ghrita helps pacify Kapha-related disorders.
24) Pain:
Various pains such as abdominal cramps or headaches are among the symptoms of Dushivisha Janya Lakshana addressed by Ajeya Ghrita.
25) Krimighna (Krmighna, Krimi-ghna):
Indicates anti-parasitic properties. Ajeya Ghrita contains ingredients like Vidanga which help in eliminating parasites.
26) Chandra:
[see source text or glossary: Chandra]
27) Vipaka:
Post-digestive effect of a substance in Ayurveda. Ajeya Ghrita primarily has Madhura Vipaka, which aids in pacifying Vata.
28) Laghu:
Property meaning lightness. Ajeya Ghrita has Laghu qualities, making it effective in treating symptoms of Dushivisha.
29) Kasa (Kasha):
Cough or respiratory symptoms. Ajeya Ghrita showed efficacy in treating Kasha (cough) associated with Dushivisha.
30) Atisara:
Diarrhea, regarded as a symptom of Dushivisha Janya Lakshana, targeted in the study using Ajeya Ghrita.
31) Virya:
Potency of a substance. Ajeya Ghrita predominantly possesses Ushna Virya, contributing to its therapeutic effects.
32) Visha (Visa):
Poison. The study aims to treat Dushivisha, a cumulative type of poison, using Ajeya Ghrita.
33) Rasa (Rasha):
Taste, an important aspect in Ayurvedic pharmacology impacting the efficacy of treatments. Ajeya Ghrita's ingredients have beneficial Rasas.
34) Samprapti:
Pathogenesis or mechanism of disease formation in Ayurveda. Ajeya Ghrita aims to counteract the Samprapti of Dushi-visha.
35) Kaphaghna (Kapha-ghna):
Property of alleviating Kapha Dosha. Ajeya Ghrita includes Kaphaghna ingredients to treat Kapha-related symptoms.
36) Ayurveda (Ayus-veda):
Traditional Indian system of medicine. The study uses Ayurvedic principles and formulations like Ajeya Ghrita to treat Dushivisha.
37) Keshya (Kesya):
Related to hair. Ingredients in Ajeya Ghrita possess Keshya properties, aiding in the treatment of hair-related symptoms.
38) Ushna (Usna):
Hot potency (Virya) which helps balance Vata and Kapha Doshas. Ajeya Ghrita contains ingredients with Ushna Virya.
39) Campu:
[see source text or glossary: Campu]
40) Blood:
Laboratory parameters like HB (hemoglobin) and TLC were used to assess the effectiveness of Ajeya Ghrita treatment.
41) Katu:
One of the six tastes (Rasas) in Ayurveda, often linked with treating Kapha Dosha. Katu Rasa is a component of Ajeya Ghrita.
42) Vata:
One of the three Doshas in Ayurveda. Ajeya Ghrita has properties that help in balancing Vata Dosha symptoms.
43) Viruddhahara (Viruddha-ahara):
Incompatible food combinations contributing to Dushivisha, treated by Ajeya Ghrita in the study.
44) Kushthaghna (Kusthaghna):
Property of treating skin diseases. Ajeya Ghrita contains ingredients with Kushthaghna properties to alleviate skin-related symptoms.
45) Smritinasha (Smrtinasa, Smriti-nasha):
Loss of memory, a symptom targeted in the study of Ajeya Ghrita's effectiveness against Dushivisha Janya Lakshana.
46) Ahitahara (Ahita-ahara):
Unwholesome food habits contributing to Dushivisha, treated using Ajeya Ghrita in the study.
47) Tiktarasa:
Bitter taste, one significant Rasa in Ajeya Ghrita's ingredients, contributing to its therapeutic effects against Dushivisha.
48) Katurasa (Katu-rasa):
Pungent taste, found in many ingredients of Ajeya Ghrita, aiding in Kapha and Dushivisha treatment.
49) Madhura:
Sweet taste, which is part of Ajeya Ghrita's Vipaka, aiding in balancing Vata Dosha.
50) Vrishya (Vrsya):
[see source text or glossary: Vrishya]
51) Snigdha:
Oily property, present in Ajeya Ghrita's ingredients, helping in pacifying Vata Dosha symptoms.
52) Samaka (Shamaka):
Pacifying property. Ajeya Ghrita's ingredients help to shamaka (control) various symptoms of Dushivisha.
53) Tikshna (Tiksna):
Sharp, penetrating quality. Ajeya Ghrita contains Tiksna ingredients to treat Kapha-related Dushivisha.
54) Tantra (Tamtra, Tantrism):
[see source text or glossary: Tantra]
55) Nausea:
Recurrent nausea is one of the symptoms tackled in the Ajeya Ghrita study for Dushivisha Janya Lakshana.
56) Nature:
[see source text or glossary: Nature]
57) Dosha (Dosa):
Imbalance causing disease in Ayurveda. Ajeya Ghrita aims to balance Doshas like Vata and Kapha involved in Dushivisha.
58) Rakta:
Blood, affected by Dushivisha. Ajeya Ghrita aims to treat conditions related to Rakta Dhatu.
59) Tikta:
Bitter taste in Ayurveda, present in Ajeya Ghrita ingredients, aiding in Kapha-related Dushivisha treatment.
60) Dhatu:
Body tissues in Ayurveda. Rakta Dhatu is particularly affected by Dushivisha, treated with Ajeya Ghrita.
61) Balya:
[see source text or glossary: Balya]
62) Crop:
Pesticides used in crop growth contribute to Dushivisha, which Ajeya Ghrita aims to counteract.
63) Burning sensation:
One of the symptoms in Dushivisha Janya Lakshana, treated by Ajeya Ghrita's properties.
64) Pharmacological:
[see source text or glossary: Pharmacological]
65) Pharmacology:
[see source text or glossary: Pharmacology]
66) Tuberculosis:
Excluded from the study's criteria, though it involves chronic toxicity similar to Dushivisha.
67) Daruharidra (Daru-haridra):
An herb used in Ajeya Ghrita with Kandughna (anti-itching) properties aiding in Dushivisha treatment.
68) Rasashastra (Rasa-shastra, Rasasastra):
[see source text or glossary: Rasa-sastra]
69) Bhadradaru (Bhadra-daru):
An ingredient in Ajeya Ghrita with Jwaraghna (antipyretic) and Kandughna properties.
70) Raktadhatu (Rakta-dhatu):
The blood tissue in Ayurveda, affected by Dushivisha; Ajeya Ghrita aims to balance Rakta Dhatu.
71) Kaphadosha (Kaphadosa, Kapha-dosha):
Dosha involved in symptoms of Dushivisha. Ajeya Ghrita helps in pacifying imbalanced Kapha.
72) Discussion:
[see source text or glossary: Discussion]
73) Kantakari (Kamtakari):
An ingredient in Ajeya Ghrita with properties to treat Krimighna, skin disorders, and Dushivisha.
74) Prasadana:
[see source text or glossary: Prasadana]
75) Goghrita (Goghrta, Go-ghrita):
[see source text or glossary: Go-ghrita]
[Note: The above list is limited to 75. Total glossary definitions available: 113]
Other Science Concepts:
Discover the significance of concepts within the article: �A Clinical Study on Efficacy of Ajeya Ghrita in Dushivisha Janya Lakshana�. Further sources in the context of Science might help you critically compare this page with similair documents:
Ayurveda, Dushivisha, Ajeya-Ghrita, Statistical analysis, Inclusion criteria, Exclusion criteria, Clinical study, Marked improvement, Patient Selection Criteria, Moderate improvement, Laboratory investigation, Complete remission, Subjective Criteria, Objective parameter, Cumulative toxicity, Health hazard, Demographic parameters, Pesticide pollution, Symptoms of Dushivisha.