Anti depressant activity of Mamsyadi Kwatha: An Ayurvedic compound formulation
Journal name: AYU (Journal of Research in Ayurveda)
Original article title: Anti depressant activity of Mamsyadi Kwatha: An Ayurvedic compound formulation
AYU is an internationally recognized quarterly journal dedicated to advancing research in Ayurveda. The journal covers a wide range of topics, including clinical and pharmacological research in Ayurveda's eight branches, herbal remedies, phytochemistry, and ethnomedicine.
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M. Shreevathsa
B. Ravishankar
Rambabu Dwivedi
AYU (Journal of Research in Ayurveda):
(An International Quarterly Journal of Research in Ayurveda)
Full text available for: Anti depressant activity of Mamsyadi Kwatha: An Ayurvedic compound formulation
Year: 2013 | Doi: 10.4103/0974-8520.115448
Copyright (license): CC BY-NC-SA 4.0
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Summary of article contents:
Depression is a psychiatric condition in which there is loss of interest in all pleasurable outlets, viz. food, sex, work, friends, hobbies and entertainment. The prevalence rate of the disease is 6-8% in women and 3-5% in men. Ayurveda, the science of life, provides systematic management principles for depression. Mamsyadi Kwatha is one such formulation stated by Yadavji Trikamji Acharya in Siddha Yoga Sangraha and Bheshaja Samhita, which is said to be effective in psychiatric conditions. The ingredients are Jatamansi (Nardostachys jatamansi), Ashwagandh (Withania somnifera) and Parasika Yavani (Hyocymus niger) in an 8:4:1 ratio, respectively. The test drug was subjected for antidepressant activity in experimental models. The models selected for anti depressant activity were behavioral despair test, anti-reserpine test and Chronic Fatigue Syndrome (CFS) test in albino mice. The test formulation showed significant inhibition of behavioural despair (P < 0.05), weak to moderate anti-reserpine activity - ptosis (P < 0.001), catatonia (P < 0.01), sedation (P < 0.01) and moderate effect in CFS test (P < 0.050). These effects clearly show that Mamsyadi Kwatha has an anti-depressant activity.
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Ayurveda, Ashvagandha, Jatamamsi, Loss of interest, Statistical analysis, Depressed mood, Diagnostic criteria, Experimental model, Antidepressant activity, Prevalence rate, Animal Ethics Committee, Behavioral despair test, Psychiatric condition, Mamsyadi Kwatha, Chronic Fatigue Syndrome, Significant weight loss, Unpaired Student's t-test, Anti-reserpine test, Immobility time.
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