Physico-chemical standardization of Sitopaladi churna
Journal name: Ancient Science of Life
Original article title: Physico-chemical standardization of Sitopaladi churna
The ANSCI is a peer-reviewed, open-access journal focused on Ayurveda and traditional medicines. It publishes original research, reviews, and literary studies linking traditional knowledge with modern science, covering disciplines like botany, ethnomedicine, pharmacology, and clinical research.
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Original source:
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Inder Kumar Makhija, Chandrashekara Shastry Shreedhara, Holavana Hally Nanjundaiah Setty Aswatha Ram
Ancient Science of Life:
(A quarterly multi-disciplinary scientific research journal in Ayurveda)
Full text available for: Physico-chemical standardization of Sitopaladi churna
Year: 2012
Copyright (license): CC BY-NC-SA
Summary of article contents:
Introduction
The study focuses on the standardization of Sitopaladi churna, a well-known Ayurvedic polyherbal formulation used for treating various respiratory ailments such as bronchitis, pneumonia, and cold-related conditions. Given the increasing interest in traditional medicines, particularly due to growing side effects from synthetic drugs, standardizing Ayurvedic formulations is essential to ensure their safety, efficacy, and reliable therapeutic outcomes. This research highlights the critical need for quality control by utilizing modern analytical techniques to assess and standardize Ayurvedic products, thereby enhancing their credibility in healthcare.
Importance of Physico-Chemical Standardization
An essential aspect of the study is the physico-chemical standardization of Sitopaladi churna through various methods, including powder microscopy, qualitative phytochemical analysis, and high-performance thin-layer chromatography (HPTLC) for quantifying key compounds—piperine and cinnamaldehyde. The study involved comparing an in-house formulated sample of Sitopaladi churna with two commercially available brands. The analytical techniques employed demonstrate a robust framework for evaluating the purity and quality of the formulation. By establishing reliable methods for quantification and characterization, the research provides a model for setting stringent quality control standards for Ayurvedic products.
Conclusion
The findings of this study underscore the significance of developing and validating standardized protocols for Ayurvedic formulations like Sitopaladi churna. The research successfully presented effective methodologies for the quantification of active compounds, contributing to the establishment of quality parameters aimed at assisting manufacturers and regulatory bodies. The study advocates for the integration of conventional and modern approaches to enhance the quality and safety of herbal medicines, thereby ensuring that they can be confidently prescribed as viable alternatives to synthetic drugs in healthcare.
FAQ section (important questions/answers):
What is Sitopaladi churna and its uses?
Sitopaladi churna is a traditional Ayurvedic polyherbal formulation used to treat conditions like pleurodynia, intercostal neuralgia, cold, cough, bronchitis, pneumonia, and chest congestion. It is highly reputed for its therapeutic efficacy.
What methods were used for the standardization of Sitopaladi churna?
The study employed various methods for standardization, including powder microscopy, physico-chemical evaluations, thin layer chromatography (TLC), and high-performance thin layer chromatography (HPTLC) fingerprinting.
What are the key active components quantified in the study?
The study focused on quantifying piperine and cinnamaldehyde, both known for their significant biological activities like anti-inflammatory and antioxidant effects using validated HPTLC methods.
What was the main conclusion of the research on Sitopaladi churna?
The research established quality control parameters and developed simple, precise HPTLC methods for piperine and cinnamaldehyde quantification, assisting manufacturers in setting standards for Sitopaladi churna.
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Traditional Indian medicine, Alternative system of medicine, High performance thin layer chromatography, Ayurvedic Formulary of India, Quantitative analysis, Sitopaladi Churna, Standard protocol, Bioactive compound, Physico-chemical standardization, Colorimetric method, Molecular structure, Quality Control Test, Microscopic characterization, Experimental Condition, Heavy metals estimation, Phytochemical constituent.