Standardization of Habbe Irqun Nisa - Unani anti-inflammatory formulation
Journal name: Ancient Science of Life
Original article title: Standardization of the finished product: Habbe Irqun Nisa - A Unani anti-inflammatory formulation
The ANSCI is a peer-reviewed, open-access journal focused on Ayurveda and traditional medicines. It publishes original research, reviews, and literary studies linking traditional knowledge with modern science, covering disciplines like botany, ethnomedicine, pharmacology, and clinical research.
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Original source:
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S. Farhan Husain, Irshad Ahmad, Shariq Shamsi
Ancient Science of Life:
(A quarterly multi-disciplinary scientific research journal in Ayurveda)
Full text available for: Standardization of the finished product: Habbe Irqun Nisa - A Unani anti-inflammatory formulation
Year: 2012
Copyright (license): CC BY-NC-SA
Summary of article contents:
Introduction
The study focuses on the Habbe Irqun Nisa (HI), a traditional Unani anti-inflammatory formulation used in treating conditions like arthritis and sciatica. While there is a growing usage of herbal medicines due to the adverse effects associated with non-steroidal anti-inflammatory drugs (NSAIDs), the need for standardization of herbal products is increasingly recognized. The objective of this work was to perform a thorough evaluation and physicochemical standardization of HI to ensure its quality and efficacy.
Standardization and Quality Control
The preparation of HI involved a meticulous process that included selecting the appropriate crude drugs, namely Sibr (Aloe barbadensis), Post Halela Zard (Terminalia chebula), and Suranjan Shirin (Colchicum autumnale). After preparing the pills, various physicochemical parameters were assessed, such as organoleptic characteristics, pH, moisture content, ash values, friability, hardness, weight variation, disintegration time, and thin layer chromatography (TLC). The results demonstrated that the pills met several pharmacopoeial standards: the average hardness was measured at 4.33 kg/cm, the moisture content was determined to be 8.17%, and a disintegration time of 32.67 minutes was recorded. Additionally, TLC analysis revealed two distinct spots with calculated Rf values of 0.42 and 0.72, indicating the purity of the ingredients used.
Conclusion
The findings from this study underscore the importance of standardization in ensuring the quality and reliability of traditional formulations like Habbe Irqun Nisa. Establishing specific physicochemical parameters can greatly aid in quality control for future herbal products, facilitating their acceptance in modern therapeutic settings. As the interest in herbal medicine grows, the formulation of robust quality control methods becomes imperative to safeguard consumer health and ensure the efficacy of these traditional systems of medicine.
FAQ section (important questions/answers):
What is Habbe Irqun Nisa used for in Unani medicine?
Habbe Irqun Nisa is an anti-inflammatory formulation used in the treatment of conditions like arthritis (Warame Mafasil) and sciatica (Irqun Nisa). It is valued for its efficacy and lesser side effects compared to non-steroidal anti-inflammatory drugs.
How is Habbe Irqun Nisa prepared and standardized?
It is prepared by blending powdered crude drugs with gum acacia as a binder, followed by drying. Standardization involves assessing physicochemical properties like moisture content, pH, and disintegration time, ensuring quality and consistency in each batch.
What are the main ingredients of Habbe Irqun Nisa?
The formulation primarily includes three ingredients: Sibr (Aloe barbadensis), Post Halela Zard (Terminalia chebula), and Suranjan Shirin (Colchicum autumnale), each contributing to its anti-inflammatory properties and overall efficacy.
What quality control tests were performed on Habbe Irqun Nisa?
Quality control tests included evaluations of organoleptic properties, moisture content, ash values, hardness, friability, disintegration time, and thin layer chromatography (TLC) to ensure purity and effectiveness of the formulation.
Other Science Concepts:
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Herbal medicine, Finished product, Quality Control, Ash value, Thin Layer Chromatography, Moisture content, Anti-inflammatory formulation, Disintegration time, Organoleptic properties, Extractive value, Unani system of medicine, Physicochemical Parameter, Weight variation test, Hardness test, Loss of weight on drying, Standardization studies, National Formulary.