Study on itr. ustukhudoos with cloves for allergic rhinitis.
Journal name: Ancient Science of Life
Original article title: Evaluation of a combination of a unani pharmacopeal preparation (itrifal ustukhudoos) with cloves (qaranfal) in allergic rhinitis � a preliminary clinical study
The ANSCI is a peer-reviewed, open-access journal focused on Ayurveda and traditional medicines. It publishes original research, reviews, and literary studies linking traditional knowledge with modern science, covering disciplines like botany, ethnomedicine, pharmacology, and clinical research.
This page presents a generated summary with additional references; See source (below) for actual content.
Original source:
This page is merely a summary which is automatically generated hence you should visit the source to read the original article which includes the author, publication date, notes and references.
Syed Asif Hussain, A.B. Khan, M.Y. Siddiqui, T. Latafat, T. Kidwai
Ancient Science of Life:
(A quarterly multi-disciplinary scientific research journal in Ayurveda)
Full text available for: Evaluation of a combination of a unani pharmacopeal preparation (itrifal ustukhudoos) with cloves (qaranfal) in allergic rhinitis � a preliminary clinical study
Year: 2003
Copyright (license): CC BY-NC-SA
Download the PDF file of the original publication
Summary of article contents:
Introduction
Allergic rhinitis is a prevalent inflammatory condition marked by symptoms such as sneezing, rhinorrhoea, nasal obstruction, and itching. This study explores the clinical efficacy of a Unani pharmacopeal preparation, Itrifal Ustukhudoos, combined with cloves (Qaranfal), in treating allergic rhinitis among patients dissatisfied with conventional antihistamines. Conducted at Ajmal Khan Tibbiya College Hospital, the study involved 20 patients aged 15 to 50 years, with the goal of evaluating the effectiveness of this herbal combination and its potential as an alternative treatment for individuals experiencing allergic rhinitis symptoms.
Clinical Efficacy of Itrifal Ustukhudoos with Qaranfal
The study presented promising results, showing an overall improvement of 50-80% in key allergic rhinitis symptoms, including nasal obstruction and sneezing. Notable improvements were attributed to the constituents of the herbal preparation, such as Chebulinic and Chebulagic acids from Halela and Balela, and bioactive compounds from Ustukhudoos that aid in mucus clearance and exhibit anti-inflammatory properties. A significant decrease (30%) in eosinophil count—indicative of allergic response—was also observed, likely due to β-caryophyllene and eugenol acetate present in cloves. These results highlight the therapeutic potential of integrating traditional Unani medicine with herbal ingredients in managing allergic rhinitis, particularly in patients who are unresponsive to conventional treatments.
Conclusion
The preliminary study illustrates that a combination of Itrifal Ustukhudoos and cloves may serve as a valuable treatment option for allergic rhinitis, supporting its clinical efficacy and providing a potential alternative for those dissatisfied with standard antihistaminic therapies. With notable improvement in symptoms and eosinophil counts, further investigations with larger sample sizes and comparative trials are necessary to validate these findings and enhance treatment strategies for allergic conditions. This exploration into Unani medicine underscores its significance in contemporary clinical practices for managing allergies and reinforces the need for integrative approaches in medical treatment.
FAQ section (important questions/answers):
What is allergic rhinitis and its common symptoms?
Allergic rhinitis is an inflammatory condition of the nose characterized by sneezing, rhinorrhoea, nasal obstruction, and may include conjunctival itching, lacrimation, and pharyngeal discomfort, often triggered by allergens.
What was the objective of the clinical study mentioned?
The study aimed to evaluate the therapeutic efficacy of a Unani preparation, Itrifal Ustukhudoos combined with cloves, in treating allergic rhinitis and addressing patient dissatisfaction with conventional antihistamines.
What were the criteria for patient inclusion in the study?
Inclusion criteria included symptoms such as sneezing and nasal obstruction, episodes' sudden occurrence, positive family history of allergic disorders, and an eosinophilic count greater than 9/cu.mm.
What improvements were observed after treatment with the Unani preparation?
Patients experienced significant improvement in symptoms such as rhinorrhoea, nasal obstruction, and sneezing, with overall enhancements of 50-80% in their clinical picture by the end of the study.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “Study on itr. ustukhudoos with cloves for allergic rhinitis.�. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Drug:
The term 'Drug' refers to substances used for medical treatment, particularly in the context of this study on allergic rhinitis. The research evaluates the efficacy of a Unani pharmacopeal formulation, Itrifal Ustukhudoos combined with Qaranfal (cloves) as a therapeutic alternative to conventional antihistamines, highlighting the importance of natural remedies in managing allergic conditions.
2) Itching:
Itching is a common symptom associated with allergic rhinitis, often manifesting in the nasal cavity, throat, and eyes. The study noted that patients experienced significant improvement (72.23%) in itching due to the Unani formulation's efficacy, which suggests its potential to relieve discomfort associated with allergic responses.
3) Terminalia chebula:
Terminalia chebula, known as Halela, is one of the key herbal constituents of Itrifal Ustukhudoos. Rich in compounds with anti-inflammatory and therapeutic properties, it likely contributes to the relief of rhinorrhoea and nasal obstruction, demonstrating the significance of traditional herbal ingredients in Unani medicine's treatment of respiratory ailments.
4) Bronchial asthma:
Bronchial asthma is a chronic inflammatory disease of the airways and was noted as a common comorbidity among the study participants, signifying atopy's role in allergic conditions. The study's observation of family histories of allergic disorders, including asthma, underlines the interconnectedness of allergic diseases within individuals' health profiles.
5) Vitis vinifera:
Vitis vinifera, commonly known as grape, contributes to Itrifal Ustukhudoos as Kishmish and Munaqqa (dried grape). It contains bioflavonoids with anti-inflammatory properties, supporting the overall therapeutic effect of the formulation on allergic rhinitis symptoms, thereby highlighting the significance of fruit-based ingredients in enhancing treatment efficacy.
6) Inflammation:
Inflammation is a primary characteristic of allergic rhinitis, leading to symptoms like sneezing, rhinorrhoea, and mucosal redness. The study measures clinical improvements related to inflammation through symptom assessment and eosinophil counts, emphasizing the Unani preparation's capacity to reduce inflammatory responses in allergic conditions through its active constituents.
7) Medicine:
Medicine pertains to the field of health care focused on diagnosing, treating, and preventing diseases. This study represents an intersection of traditional Unani medicine and contemporary clinical practices, showcasing how holistic approaches can address common conditions like allergic rhinitis, addressing patient dissatisfaction with conventional treatments.
8) Emblica officinalis:
Emblica officinalis, or Amla, is a vital ingredient in Itrifal Ustukhudoos. It is known for its rich antioxidant properties and potential health benefits, contributing to the formulation's effectiveness against allergic rhinitis by supporting immune function and reducing inflammation, thereby fostering a broader understanding of herbal applications in modern medicine.
9) Tuberculosis:
Tuberculosis, a serious infectious disease, is excluded from the study participants� eligibility criteria. This ensures that the assessment of the Unani preparation's effects on allergic rhinitis is not confounded by the complications of chronic respiratory diseases, thereby refining the focus of the study on allergic conditions without overlapping comorbidities.
10) Discussion:
Discussion is crucial in a research study as it contextualizes findings, linking results to existing literature and clinical significance. In this study, the discussion interprets clinical outcomes, compares them with established medical knowledge, and suggests directions for future research, ultimately aiming to enhance understanding and treatment of allergic rhinitis.
11) Science (Scientific):
Science refers to the systematic study of the structure and behavior of the physical and natural world through observation and experimentation. This study exemplifies scientific inquiry by applying traditional knowledge (Unani medicine) to investigate its efficacy against allergic rhinitis, combining empirical evidence with historical practices in medicine.
12) Khali (Khalī):
Khali (or 'khalis') pertains to purity. In the context of the study, it describes 'Shahad khalis' or pure honey, an ingredient in Itrifal Ustukhudoos. Honey is often used in traditional remedies for its therapeutic properties, emphasizing the formulation's focus on employing pure, natural substances to enhance health outcomes.
13) Honey:
Honey, particularly the pure form ('Shahad khalis') listed in the study, is recognized for its medicinal properties, including anti-inflammatory and soothing effects on mucus membranes. Its inclusion in the Unani formulation illustrates the combination of natural ingredients to harness their synergistic effects in managing allergic rhinitis symptoms effectively.
Other Science Concepts:
Discover the significance of concepts within the article: �Study on itr. ustukhudoos with cloves for allergic rhinitis.�. Further sources in the context of Science might help you critically compare this page with similair documents:
Family history, Aggravating factors, Clinical efficacy, Age distribution, Allergic Rhinitis, Double-blind trial, Antihistamine, Environmental allergen, Symptoms of Allergic Rhinitis, Preliminary Clinical Study.