Pharmacognostical and phytochemical investigation of peristrophe bicalyculata
Journal name: Ancient Science of Life
Original article title: Pharmacognostical and phytochemical investigation of peristrophe bicalyculata
The ANSCI is a peer-reviewed, open-access journal focused on Ayurveda and traditional medicines. It publishes original research, reviews, and literary studies linking traditional knowledge with modern science, covering disciplines like botany, ethnomedicine, pharmacology, and clinical research.
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Original source:
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N.V. Satyanarayana, S.H. Lachake, M.G. Chauhan
Ancient Science of Life:
(A quarterly multi-disciplinary scientific research journal in Ayurveda)
Full text available for: Pharmacognostical and phytochemical investigation of peristrophe bicalyculata
Year: 1993
Copyright (license): CC BY-NC-SA
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Summary of article contents:
Introduction
Peristrophe bicalyculata, familiarly known as Kakjangha in Sanskrit and Kaliadhedi in Gujarat, is an annual herb native to India, traditionally utilized for its therapeutic properties, particularly in treating tuberculosis and as a remedy for sprains and fractures. This study conducted a comprehensive pharmacognostical and phytochemical investigation of the root and stem of the herb, revealing the presence of various bioactive compounds such as coumarins, alkaloids, and saponins, which had not been documented in this species before. The research aimed to confirm the authenticity of the plant and to explore its chemical constituents in relation to its medicinal applications.
Pharmacological Potential of Peristrophe bicalyculata
The detailed phytochemical screening of Peristrophe bicalyculata highlighted several important compounds contributing to its medicinal properties. The investigation identified alkaloids, coumarins, potassium chloride, and saponins prominently in the root and stem. Moreover, the study indicated the potential antibacterial activity of the aqueous extract of the herb and its Kshara (aqueous ash extract), suggesting that the plant could play a significant role in herbal medicine due to its wide range of therapeutic properties. The study also addressed the morphological and histological characteristics of the plant, enhancing the understanding of its structure and reinforcing its identification against other similar species.
Conclusion
This research underscores the pharmacological significance of Peristrophe bicalyculata and validates its traditional use in various medicinal applications. The novel findings regarding its phytochemicals pave the way for further investigations into its antibacterial properties and the potential development of herbal formulations. By elucidating the plant's chemical constituents, the study contributes valuable insights into its therapeutic efficacy and encourages additional research to explore its capabilities in contemporary medicine. Overall, Peristrophe bicalyculata stands out as an important herb worth further exploration in both scientific and traditional healthcare contexts.
FAQ section (important questions/answers):
What is Peristrophe bicalyculata commonly known as in India?
Peristrophe bicalyculata is commonly referred to as Kakjangha in Sanskrit and Kaliadhedi in Gujarat. It is an annual herb widely distributed throughout India.
What therapeutic properties does Peristrophe bicalyculata possess?
The herb is known for various therapeutic properties, including expectorant, analgesic, anti-inflammatory, antipyretic, and antibacterial effects. It is traditionally used for treating conditions like tuberculosis and sprains.
What compounds were discovered in Peristrophe bicalyculata for the first time?
The study identified the presence of coumarins, alkaloids, potassium chloride, saponins, and free sugars in the stem and root of Peristrophe bicalyculata for the first time.
What methods were used for phytochemical screening of the plant?
Phytochemical screening involved solvent extraction, TLC separation, and various chemical tests to isolate compounds like alkaloids, coumarins, saponins, and other constituents from the root and stem.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “Pharmacognostical and phytochemical investigation of peristrophe bicalyculata�. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Phytochemical:
Phytochemical refers to naturally occurring chemical compounds found in plants. These compounds often play significant roles in plant physiology and can attract or deter herbivores. In the context of Peristrophe bicalyculata, various phytochemicals such as alkaloids and coumarins were identified, linking to its potential therapeutic properties.
2) Sugar:
Sugar, especially in a phytochemical context, relates to simple carbohydrates that can be naturally extracted from plants. In this study, free sugars isolated from the root of Peristrophe bicalyculata were reported, which may contribute to the plant's energy storage and potential medicinal benefits.
3) Water:
Water is essential for life and acts as a solvent in many biological processes. In pharmacognosy, the extraction of phytochemicals often involves the use of water. The mention of aqueous extracts, such as 'Kshara', implies its role in extracting the active constituents from Peristrophe bicalyculata for medicinal evaluation.
4) Antibiotic (Antibacterial):
Antibacterial describes properties that inhibit bacterial growth. The study highlights the antibacterial activity of Peristrophe bicalyculata, suggesting its use in traditional medicine for infections. Various constituents, including phytochemicals, are evaluated for their efficacy against bacteria, supporting its traditional usage in treating ailments.
5) Activity:
Activity in this context refers to the biological effects of compounds, especially their medicinal properties. The investigation into the antibacterial activity of Peristrophe bicalyculata illustrates the relevance of assessing how the plant’s constituents interact with biological systems to potentially inhibit disease.
6) Pharmacognostical:
Pharmacognostical pertains to the study of medicinal drugs derived from natural sources. This investigation into Peristrophe bicalyculata is pharmacognostical in nature, focusing on the identification and composition of phytochemicals that impart therapeutic effects, enhancing understanding of its traditional medicinal applications.
7) Tuberculosis:
Tuberculosis (TB) is a serious infectious disease primarily affecting the lungs. The traditional use of Peristrophe bicalyculata for treating TB indicates its relevance in folk medicine. The study's emphasis on the antitubercular activity of specific phytochemicals supports exploring its potential as a therapeutic agent.
8) Discussion:
Discussion refers to the interpretation and analysis of findings. The discussion section of the study evaluates the morphological, microscopical, and phytochemical results obtained from Peristrophe bicalyculata, allowing the authors to contextualize their findings within existing botanical and pharmacological knowledge for further research.
9) Science (Scientific):
Science represents systematic knowledge achieved through observation and experimentation. The multidisciplinary approach taken in studying Peristrophe bicalyculata combines botany, pharmacognosy, and phytochemistry, leading to scientific insights on traditional medicines, and providing a basis for future medicinal research.
10) Kshara (Ká¹£Ära):
Kshara is an Ayurvedic term that describes an aqueous extract of ashes, traditionally used for therapeutic purposes. In this research, the mention of Kshara underscores its role in evaluating the medicinal efficacy of Peristrophe bicalyculata, as it may enhance the extraction of bioactive compounds.
11) Vasaka (VÄsaka, Vashaka, VaÅ›akÄ, VÄÅ›aka):
Vasaka refers to the plant Adhatoda vasica, known for its medicinal properties, particularly in treating respiratory disorders. The comparison to Peristrophe bicalyculata highlights the shared traditional uses of these herbs in herbal medicine, reinforcing the importance of botanical classification in pharmacognosy.
12) Liquor:
Liquor in this context likely refers to a concentrated solution resulting from the extraction of phytochemicals using solvents. The study involves aqueous extracts and describes processes that yield pharmacologically active compounds, thereby providing insight into methods of preparing herbal medicines.
13) Botany:
Botany is the scientific study of plants, encompassing various aspects such as structure, function, and chemistry. The research into Peristrophe bicalyculata involves botanical classification and morphological analysis, emphasizing the significance of understanding plant diversity in the exploration of traditional remedies.
14) Hand:
Hand here may refer to the manual techniques used in preparing and examining plant material for the study. Free hand sections of the stem and root were utilized for histological observations, demonstrating the importance of hands-on methodologies in botanical and pharmacognostical research.
15) Worm:
Worm in this study describes an organism found within the roots of Peristrophe bicalyculata, possibly indicating a pathological condition affecting the plant. Recognizing such infestations can aid in understanding plant health and may inform medicinal extraction practices, emphasizing ecological interactions.
16) Salt (Salty):
Salt, in the context of this study, likely refers to inorganic salts present in the plant. Potassium chloride was identified in Peristrophe bicalyculata, suggesting the mineral content that may influence the overall physiological and therapeutic properties of the herb.
Other Science Concepts:
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