A preliminary study on the effect of tinospora cordifolia on mitosis
Journal name: Ancient Science of Life
Original article title: A preliminary study on the effect of tinospora cordifolia on mitosis
The ANSCI is a peer-reviewed, open-access journal focused on Ayurveda and traditional medicines. It publishes original research, reviews, and literary studies linking traditional knowledge with modern science, covering disciplines like botany, ethnomedicine, pharmacology, and clinical research.
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Original source:
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R. Y. Abhanga, P. P. Jogleker, P. H. Kulkarni
Ancient Science of Life:
(A quarterly multi-disciplinary scientific research journal in Ayurveda)
Full text available for: A preliminary study on the effect of tinospora cordifolia on mitosis
Year: 1991
Copyright (license): CC BY-NC-SA
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Summary of article contents:
Introduction
The study conducted by R. Y. Abhang, P. P. Jogleker, and P. H. Kulkarni aimed to evaluate the mitotic effects of the Ayurvedic plant Tinospora cordifolia, commonly known as Guduci, using the onion root tip as a test system. Guduci is traditionally recognized in Ayurveda for its rejuvenating properties and potential metabolic benefits. The study sought to explore its presumed ability to stimulate cellular activity and metabolism through a systematic examination of its effects on mitosis.
Impact on Mitosis
The experiment involved preparing an aqueous extract of Tinospora cordifolia and assessing its impact on the mitotic activity of onion root cells. The study compared the percentages of cells undergoing mitosis in onions exposed to the aqueous extract, an alcoholic extract, and a control group treated with water. Results indicated a statistically significant increase in mitotic activity in the aqueous extract group, whereas the alcoholic extract resulted in a statistically significant decrease. This finding suggests that the aqueous extract of Guduci may possess mitosis-stimulating properties, highlighting its potential as a therapeutic agent.
Conclusion
The results from this preliminary study indicate that Tinospora cordifolia has a notable impact on mitosis, particularly with its aqueous extract leading to enhanced cellular division. Although these findings offer valuable insights into the plant鈥檚 medicinal properties, further research using additional mitotic testing systems is necessitated to confirm its mitotic-stimulating activities. The onion root tip system proves to be an effective methodology for initial evaluations of the metabolic properties of various medicinal plants, indicating the need for continued exploration in this area.
FAQ section (important questions/answers):
What is the purpose of the study on Tinospora cordifolia?
The study aimed to evaluate the mitosis-stimulating effects of Tinospora cordifolia using onion root tip cells as the test system.
How was the aqueous extract of Tinospora cordifolia prepared?
The aqueous extract was made by removing alcohol from the tincture and replacing it with distilled water, which was then used for the experiment.
What significant results were found regarding mitosis after treatment?
The aqueous extract showed a statistically significant increase in mitotic activity, while the alcoholic extract showed a significant decrease, indicating differing effects of the extracts.
What was the conclusion of the researchers regarding the effects observed?
The study suggested that Tinospora cordifolia might possess mitosis-stimulating activity, but further research is needed to confirm these findings through additional testing.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for 鈥淎 preliminary study on the effect of tinospora cordifolia on mitosis鈥�. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Water:
Water serves as a crucial solvent in biological processes and is essential for life. In the context of the study, distilled water was used to prepare the aqueous extract of Tinospora cordifolia, which demonstrated significant mitotic activity in the onion root tip experiment. Its role underscores the importance of hydration in experimental settings.
2) Activity:
Activity refers to the functional processes occurring within biological systems. In this study, mitotic activity pertains to the division of cells, crucial for growth and regeneration. The measured increase in mitotic activity upon treatment with the aqueous extract suggests potential therapeutic properties of Tinospora cordifolia, meriting further investigation.
3) Tinospora cordifolia:
Tinospora cordifolia, commonly known as Guduci, is a medicinal plant touted for its rejuvenating effects in Ayurveda. The study investigates its potential to stimulate cell division, as indicated by the increased mitotic activity observed in onion root tips. This highlights its relevance in both traditional and modern medicine.
4) Guduci (Gu岣島ci, Gu岣嵟玞i, Gu岣嵟玞墨, Gu岣島c墨):
Guduci, or Tinospora cordifolia, is revered in Ayurvedic medicine for its health-promoting properties. Considered a rasayani, it is believed to rejuvenate and restore youthfulness. In the study, Guduci's aqueous extract significantly affected mitotic activity, showcasing its potential as a herbal remedy with metabolic benefits.
5) Drug:
The term 'drug' in this context refers to a substance used for therapeutic purposes. The aqueous extract of Tinospora cordifolia was characterized as a drug in the evaluation of its effects on mitosis. This classification is essential for understanding its pharmacological implications and therapeutic potential.
6) Inference:
Inference involves drawing conclusions based on observed data. In the study, the authors inferred that the aqueous extract of Tinospora cordifolia possesses mitosis-stimulating activity due to the significant increase in cell division percentages. Such inferences are foundational in scientific research, guiding further experiments and hypotheses.
7) Ayurveda (膧yurveda, Ayus-veda):
Ayurveda is an ancient system of medicine from India that emphasizes balance in bodily systems through diet, herbal treatment, and yogic breathing. Tinospora cordifolia, categorized as a rasayani in Ayurveda, is believed to rejuvenate the body, and this study aligns traditional knowledge with modern scientific inquiry into its effects.
8) Rasayani (Ras膩yan墨):
Rasayani is a classification in Ayurvedic medicine referring to rejuvenating agents. These substances are thought to promote longevity and restore vitality. The study's focus on Tinospora cordifolia as a rasayani connects traditional Ayurvedic practices with contemporary scientific investigations into cellular regeneration and health enhancement.
9) Medicine:
Medicine encompasses the science and practice of diagnosing, treating, and preventing disease. This study embodies the intersection of traditional herbal remedies and modern scientific approaches, as it evaluates the cellular impacts of Tinospora cordifolia and contributes to the broader understanding of its medicinal properties.
10) Science (Scientific):
Science represents systematic efforts to build and organize knowledge based on empirical evidence. The study exemplifies scientific methodology by employing the onion root tip mitosis test to assess the effects of Tinospora cordifolia, thus bridging traditional herbal medicine with scientific validation.
11) Jnana (J帽膩na):
Jnana, meaning knowledge or wisdom in Sanskrit, plays a pivotal role in both Ayurveda and scientific investigation. In this context, Jnana can refer to the understanding of medicinal plants and their properties, such as those elucidated in this study regarding the potential health benefits of Tinospora cordifolia.
Other Science Concepts:
Discover the significance of concepts within the article: 鈥�A preliminary study on the effect of tinospora cordifolia on mitosis鈥�. Further sources in the context of Science might help you critically compare this page with similair documents:
Ayurveda, Dhatuposhana, Tridoshashamana, Tinospora cordifolia, Experimental design, Statistically Significant, Aqueous extract, Preliminary study, Alcoholic extract, Cell cycle, Light microscope, Mitotic activity.