Significance of Recombinant DNA technology
Recombinant DNA technology is a biotechnological method that involves manipulating genetic material to produce various substances, including therapeutic proteins and biosimilars. By joining DNA segments from different sources, this technology enables the production of specific proteins such as insulin glargine, tissue plasminogen activator, and enzymes like α-amylases. It plays a crucial role in creating genetically modified organisms and facilitates advancements in both medical and agricultural fields, allowing for the development of innovative treatments and products.
Synonyms: Genetic engineering, Molecular cloning, Gene manipulation, Genetic modification, Genetic alteration, Biotechnology.
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The concept of Recombinant DNA technology in scientific sources
Recombinant DNA technology enables the alteration of DNA to produce specific proteins, essential for human healthcare, by utilizing techniques to combine DNA segments from diverse sources for genetic manipulation.
From: World Journal of Pharmaceutical Research
(1) A technology used to manipulate DNA for various applications in biotechnology and medicine, increasing the demand for freeze-drying in pharmaceutical production.[1] (2) A method of producing insulin glargine that involves the substitution of glycine for asparagine at position A21 of the insulin molecule.[2] (3) A set of techniques used to join together DNA segments in a cell-free system, often leading to gene cloning and the production of genetically modified organisms.[3] (4) A genetic engineering method used to manipulate and combine DNA sequences from different sources to produce specific proteins or enzymes.[4] (5) A technology that allows for the cloning and expression of genes, facilitating the production of enzymes like α-amylases in various organisms.[5]
From: Journal of Indian Society of Periodontology
(1) A molecular biology technique used to produce recombinant proteins such as rhBMP-2.[6]