Significance of Oncogenesis
Oncogenesis refers to the process of tumor formation, where normal cell functions are altered, resulting in cancer development. It involves the formation of non-random extrachromosomal elements and is linked to molecular themes in cancer research. Human Papillomavirus (HPV) can initiate oncogenesis by interacting with environmental factors, contributing to the transformation of normal cells into cancerous ones. This process often activates telomerase or alternative mechanisms for telomere lengthening, further supporting tumor progression.
Synonyms: Carcinogenesis, Tumorigenesis, Cancer development, Malignant transformation, Neoplastic development, Neoplasia
The below excerpts are indicatory and do represent direct quotations or translations. It is your responsibility to fact check each reference.
The concept of Oncogenesis in scientific sources
Oncogenesis is the transformation of normal cells into cancer cells, typically involving mechanisms like the activation of telomerase or alternative lengthening of telomeres, which play crucial roles in cancer development and progression.
From: The Malaysian Journal of Medical Sciences
(1) The formation of non-random extrachromosomal elements can be associated with this process, as it is observed during development and differentiation.[1] (2) This term is associated with molecular themes, and it is related to the study of cancer development and progression, and a specific article focuses on the molecular aspects.[2] (3) HPV acts as the initiator of this process, requiring interaction with somatic environmental factors to cause cancer in the human body and trigger this biological mechanism.[3] (4) The process of tumor formation, wherein normal cellular processes become altered to support cancer development.[4]