Significance of Formulation Development
Formulation Development involves a comprehensive process aimed at creating effective drug formulations that achieve desired therapeutic effects while ensuring safety and efficacy. This includes designing and preparing pharmaceutical products tailored for optimal drug release, stability, and absorption. Key components of formulation development may include combinations of active ingredients and excipients, with specific techniques to enhance drug solubility and effectiveness. It encompasses various methodologies and is critical in developing diverse pharmaceutical forms, such as floating microballoons and transdermal patches, to improve clinical efficacy.
Synonyms: Formulation design, Formulation optimization, Formulation strategy, Product formulation
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The concept of Formulation Development in scientific sources
Formulation Development involves designing pharmaceutical formulations to improve solubility, dissolution rates, and stability, aiming for effective drug release profiles. It also focuses on optimizing drug compositions to enhance therapeutic efficacy.
From: World Journal of Pharmaceutical Research
(1) The process of creating a specific pharmaceutical formulation that optimizes the release and absorption of a drug, such as Tadalafil.[1] (2) Formulation development is the process of creating a pharmaceutical product, including the integration of various agents to achieve desired characteristics like stability and release profiles.[2] (3) The process of creating a drug formulation with the appropriate composition and attributes to achieve desired therapeutic effects.[3] (4) The process of creating a drug formulation that contains the active drug substance and any other components required for therapeutic use.[4] (5) The overall process of creating a pharmaceutical product, including the selection and combination of excipients and active ingredients to ensure desired therapeutic outcomes.[5]
From: Ancient Science of Life
(1) The process of creating a stable product using various ingredients, in this case focusing on Churnas containing natural sweeteners and nutraceuticals.[6]
From: Ayushdhara journal
(1) The process of designing and creating effective and safe products, including those based on Aqarqarha, to deliver therapeutic benefits.[7]