Significance of EGFR
EGFR stands for Epidermal Growth Factor Receptor, a key target in cancer treatments, particularly in bladder cancer and head and neck squamous cell carcinoma (HNSCC). This receptor is significant for cell proliferation and tumor development. Additionally, EGFR can also refer to Estimated Glomerular Filtration Rate, an important measure of kidney function used to evaluate chronic kidney disease (CKD). It assesses kidney health based on factors like serum creatinine levels, age, gender, and race to determine how effectively the kidneys filter waste from the blood.
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The concept of EGFR in scientific sources
EGFR, or Estimated Glomerular Filtration Rate, is a crucial indicator of kidney function, helping to assess the severity of kidney disease by estimating how well the kidneys filter blood.
From: The Malaysian Journal of Medical Sciences
(1) A receptor that is often amplified and overexpressed in cancer cells, particularly in gliomas, and its downstream pathways play a role in promoting survival.[1] (2) This is the abbreviation for estimated glomerular filtration rate, which is used as a measure of kidney function in the study, as described in the text.[2] (3) This is an estimate of the glomerular filtration rate that is calculated using serum creatinine and cystatin C, indicating kidney function.[3] (4) Estimated Glomerular Filtration Rate, a measure used to assess kidney function based on serum creatinine concentration and other factors.[4]