Significance of Disintegration
Disintegration is a critical process in pharmaceuticals where tablets break down into smaller particles, facilitating the release of the active ingredient. This process occurs in a liquid medium, influencing how effectively the drug is released for absorption. Overall, disintegration ensures that tablets fragment into fine particles or granules, enabling the drug to dissolve and become available in solution for therapeutic action.
Synonyms: Fracture, Fragmentation, Decomposition, Dissolution, Collapse, Splitting, Scattering, Decay
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The concept of Disintegration in scientific sources
Disintegration is the process where tablets break down into fine particles or granules in a liquid medium, facilitating drug release. This critical step affects the efficacy and absorption of the medication.
From: World Journal of Pharmaceutical Research
(1) The process where tablets break down into smaller particles to release the active pharmaceutical ingredient in a suitable form.[1] (2) The process by which tablets break down into smaller particles or granules so that the drug can be released in solution.[2] (3) The process by which a tablet breaks down into fine particles in a liquid medium, affecting drug release.[3]