Significance of Disc diffusion method
The disc diffusion method is a widely used laboratory technique that evaluates the effectiveness of antimicrobial agents by measuring the zones of inhibition around discs impregnated with test substances. This method assesses both antibacterial and antifungal activities against specific microorganisms by placing the discs on agar plates inoculated with bacteria or fungi. By analyzing the inhibition zones, researchers can determine the susceptibility of various strains to different antimicrobial agents, making this method crucial in microbiological studies.
Synonyms: Antibiotic susceptibility testing, Disk diffusion assay, Kirby-bauer test, Antimicrobial susceptibility testing
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The concept of Disc diffusion method in scientific sources
The Disc diffusion method evaluates antibacterial activity by measuring inhibition zones around discs containing test substances, allowing laboratory assessment of their antimicrobial effectiveness against specific bacterial strains.
From: The Malaysian Journal of Medical Sciences
(1) This is a technique used to determine the susceptibility of bacteria to antibiotics, and it was employed in the study to evaluate the antimicrobial resistance of the isolates.[1] (2) The disc diffusion method is another technique used to assess the antibacterial properties of substances, where the substance diffuses into the agar medium and inhibits bacterial growth.[2] (3) A lab technique used to determine the antibiotic susceptibility of bacteria by observing the inhibition of growth around antibiotic-impregnated discs.[3] (4) A laboratory technique used to assess the susceptibility of bacteria to specific antibiotics using paper discs impregnated with antibiotics.[4]