Significance of Chronic toxicity studies
Chronic toxicity studies are essential for assessing the long-term effects and safety of substances through extended exposure. These studies evaluate the safety of Tamra Bhasma, ensuring its suitability for consistent therapeutic use. They also include protocols for investigating the effects of Chlorpyrifos in experimental models like mice, focusing on the histological and biochemical changes that occur over several weeks. Overall, chronic toxicity studies play a crucial role in confirming the safety of various substances over time.
Synonyms: Long-term toxicity studies
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The concept of Chronic toxicity studies in scientific sources
Chronic toxicity studies involve investigating the long-term effects of substances, such as Chlorpyrifos in mice and Tamra Bhasma in therapeutic contexts, assessing associated histological and biochemical changes to ensure safety and efficacy over time.
From: Ancient Science of Life
(1) Investigations to determine the harmful effects of a substance following prolonged exposure.[1] (2) Chronic toxicity studies assess the long-term effects and safety of substances over extended periods of exposure in experimental subjects.[2]
From: AYU (Journal of Research in Ayurveda)
(1) Chronic toxicity studies evaluate the long-term effects of using Tamra Bhasma over extended periods to confirm its safety for consistent therapeutic use.[3]
From: World Journal of Pharmaceutical Research
(1) Investigation protocols to study the long-term effects of Chlorpyrifos administration in mice, assessing histological and biochemical changes over several weeks.[4]