Significance of Causality assessment
Causality assessment is a critical process used to evaluate whether a specific drug caused an adverse drug reaction (ADR). It involves systematic evaluations, often utilizing standardized scales like the WHO and Naranjo scales, to determine the likelihood and strength of the relationship between the drug and the observed adverse event. This method is essential for pharmacovigilance, as it helps in identifying potential safety concerns associated with medications and enhances overall patient safety.
Synonyms: Causal analysis
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The concept of Causality assessment in scientific sources
Causality assessment is an evaluation process that determines the likelihood and relationship between a specific medication and its potential adverse reactions or events, helping to establish causation in pharmacovigilance.
From: World Journal of Pharmaceutical Research
(1) The determination of whether a drug caused a particular adverse drug reaction.[1] (2) Causality assessment is the process of determining the strength of the relationship between drug exposure and the occurrence of adverse reactions.[2] (3) The process of evaluating the relationship between a drug and the observed adverse reaction, often using established scales like WHO-UMC and Naranjo scale.[3] (4) Causality assessment refers to the evaluation process to determine the relationship between a drug exposure and an adverse event, though no single method for this is universally accepted.[4] (5) The process of determining the relationship between the occurrence of an adverse drug reaction and the administration of a drug.[5]
From: Ancient Science of Life
(1) A methodology used to determine the relationship between drug administration and resulting adverse events.[6]