Significance of Biosynthesis
Biosynthesis is the process by which living organisms produce complex compounds from simpler ones, playing a crucial role in the formation of secondary metabolites. In the context of cancer, Cancer-associated fibroblasts (CAFs) lack the ability to utilize metabolites from aerobic glycolysis, leading them to secrete these metabolites to adjacent tumor cells that use them for biosynthesis, thus supporting tumor growth and metastasis. Additionally, biosynthesis occurs in plants, such as Acacia catechu, leading to bioactive compound formation.
Synonyms: Biological synthesis, Biological production, Natural synthesis, Metabolic synthesis, Formation, Creation, Synthesis, Generation, Construction
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The concept of Biosynthesis in scientific sources
Biosynthesis is the natural process involving cellular machinery to create complex compounds, playing a crucial role in understanding the biological activity of these derivatives, as indicated by regional sources.
From: The Malaysian Journal of Medical Sciences
(1) CAFs lack the ability to use the metabolites of aerobic glycolysis for biosynthesis, so these metabolites are secreted to the adjacent tumour cells, which then consume them and use them as biosynthesis factors to support tumour growth and metastasis.[1]