Significance of Antioxidant enzyme
Antioxidant enzymes are proteins that play a crucial role in combating oxidative stress by neutralizing free radicals and protecting cells from damage. Key examples include superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx). Their activity is vital in various contexts, such as assessing the effects of treatments or understanding cellular responses to stressors like paracetamol or oxidative insults. Overall, these enzymes contribute significantly to cellular health and the mitigation of oxidative damage across different tissues.
Synonyms: Free radical scavenger, Enzymatic antioxidant, Catalase, Superoxide dismutase, Glutathione peroxidase, Thioredoxin reductase
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The concept of Antioxidant enzyme in scientific sources
Antioxidant enzymes, including superoxide dismutase (SOD) and catalase (CAT), play a crucial role in protecting cells from oxidative damage by neutralizing reactive oxygen species and free radicals, particularly in the context of Carissa carandas.
From: The Malaysian Journal of Medical Sciences
(1) These, such as SOD, CAT, and glutationperoxidase, are increased by melatonin, thereby reducing oxidative stress and protecting cells from damage.[1] (2) These are enzymes that help neutralize free radicals, and the text mentions examples such as SOD and GPx, which are part of the antioxidant defense mechanisms.[2] (3) Administration of metformin, glibenclamide, and repaglinide exhibited a significant reduction in MDA concentration and considerable improvement in the altered activities of these, and markers of these are found in patients with type 2 diabetes.[3] (4) Antioxidant enzymes, such as superoxide dismutase, are mentioned as being affected by free radicals and increased by SCGO, as mentioned in the text.[4] (5) Antioxidant enzymes, such as superoxide dismutase (SOD), catalase, NAD (P) H: quinone oxidoreductase-1 (NQO-1), heme oxygenase-1 (HO-1), glutathione peroxidase (GPx) and glutathione reductase (GR), are enhanced by vitexin.[5]